Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens

Pranaya, P and Akila Devi, D (2019) Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens. International Journal of Research in Pharmaceutical Sciences, 10 (4). pp. 3475-3480. ISSN 0975-7538

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Abstract

Olax scandensRoxb. (familyOlacaceae)Available in throughout tropicalIndia. The current study, aerial parts of different concentrates ofOlax scan-denswas evaluated for itsin-vitroantioxidant potential by Diphenylpicryl-hydrazyl activity, superoxide scavenging activity, iron chelating activity tak-ing ascorbate, quercetin & Ethylenediamine tetraacetate as the standard cor-respondingly. An IC50value was originated that methanolic concentratesofOlax scandensis more efβicient in Diphenylpicrylhydrazyl radical, superox-ide radical activity, Iron chelating capacity compared EA & PE concentrates.The methanolic concentrates ofOlax scandens& ascorbate exhibited antiox-idant potential possessing IC50226�g/ml & 66�g/ml (DPPH). 185�g/ml& 60�g/ml (Superoxide) , 287�g/ml & 65�g/ml (iron-chelating Activity)respectively. Invitro antioxidant studies obviously show methanolic concen-trates ofOlax scandenshave better antioxidant activity. These results indi-cate that aerial parts of methanolic concentratesOlax scandenscould serve asa natural antioxidant, which may be useful in preventing free radical-induceddiseases.

Item Type: Article
Subjects: Pharmacy Practice > Pharmaceutics
Domains: Pharmacy Practice
Depositing User: Mr IR Admin
Date Deposited: 25 Aug 2025 07:23
Last Modified: 25 Aug 2025 07:23
URI: https://ir.vistas.ac.in/id/eprint/8981

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