M, Mohmed Najem and D., Mukilan and S., Jayakumari (2020) Safety and Efficacy of Lornoxicam and Diclofenac in Patients with Post Traumatic Pain- A Review. Journal of Evolution of Medical and Dental Sciences, 9 (24). pp. 1827-1833. ISSN 22784748
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Abstract
BACKGROUND
Post-traumatic pain after a traumatic injury is common. Physical injury or injury can bring about huge harm to your tissues and bones. All things considered, experiencing ceaseless pain after a horrible physical issue isn't bizarre. In fact, it is routinely expected after absurd injuries, for instance, those bolstered in an accident.
Non-steroidal anti-inflammatory drugs usually abbreviated as NSAIDs, are the drugs with analgesic, antipyretic and in higher doses, with anti-inflammatory effects. NSAIDs inhibit cyclooxygenase (COX) 1 and 2. Similar to other NSAIDs, diclofenac is associated with serious dose-dependent gastrointestinal, cardiovascular, and renal adverse effects. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) class of the phenylacetic acid with anti-inflammatory, pain relieving, and antipyretic properties. So, the side effects are the symptoms created because of cyclooxygenase
inhibitory action. Lornoxicam has been studied to be used in post-traumatic pain, Lornoxicam is a strong analgesic and, NSAID of the oxicam class with better tolerability profile when contrasted with different NSAIDs. New drug products
comprising of diclofenac potassium salt were related with quicker absorption and fast onset of pain relief. It has been shown to be effective in the treatment of postoperative pain, spine surgery, post cardiac surgery, and rheumatoid arthritis (RA). However, there are just a couple of studies accessible in literature looking at post employable pain-relieving impacts of lornoxicam and diclofenac. In this manner, the current review was substantiated to validate and compare the pain- relieving safety and efficacy of lornoxicam and diclofenac in intense post traumatic
pain.
Item Type: | Article |
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Subjects: | Pharmacy Practice > Pharmaceutics |
Divisions: | Pharmacy Practice |
Depositing User: | Mr IR Admin |
Date Deposited: | 09 Sep 2024 05:23 |
Last Modified: | 09 Sep 2024 05:23 |
URI: | https://ir.vistas.ac.in/id/eprint/5255 |