Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens

Study of in-vitro antioxidant activity of various extracts of aerial parts of Olax scandens Pranaya P Akila Devi D

Olax scandensRoxb. (family Olacaceae) Available in throughout tropical India. The current study, aerial parts of different concentrates of Olax scandenswas evaluated for its in-vitro antioxidant potential by Diphenylpicrylhydrazyl activity, superoxide scavenging activity, iron chelating activity taking ascorbate, quercetin & Ethylenediamine tetraacetate as the standard correspondingly. An IC50 value was originated that methanolic concentrates of Olax scandensis more efficient in Diphenylpicrylhydrazyl radical, superoxide radical activity, Iron chelating capacity compared EA & PE concentrates. The methanolic concentrates of Olax scandens & ascorbate exhibited antioxidant potential possessing IC50 226µg/ml & 66µg/ml (DPPH). 185µg/ml & 60µg/ml (Superoxide) , 287µg/ml & 65µg/ml (iron-chelating Activity) respectively. Invitro antioxidant studies obviously show methanolic concentrates of Olax scandens have better antioxidant activity. These results indicate that aerial parts of methanolic concentrates Olax scandenscould serve as a natural antioxidant, which may be useful in preventing free radical-induced diseases.
11 06 2019 3475 3480 https://creativecommons.org/licenses/by-nc-nd/4.0/ 10.26452/ijrps.v10i4.1664 https://pharmascope.org/index.php/ijrps/article/view/1664 https://pharmascope.org/index.php/ijrps/article/download/1664/2372 https://pharmascope.org/index.php/ijrps/article/download/1664/2372