Applications of fungal based nanoparticles in cancer therapy– A review

Cancer is a major cause of cancer-related mortality worldwide. Ongoing research into the development of nanomedicine includes the use of fungi, which have aided humans in their fight against cancer owing to their effortless and abundant aids. Existing clinical treatments for various types of tumors are ineffective, resulting in significant side effects and setbacks. In pharmaceutical, medical, and biomedical paradigms, the creation of nanoparticles (NPs) from fungal entities has been viewed as a promising approach recently. Different biological properties are the most prominent curative applications of the recently developed microbial based NPs for cancer treatment. Compounds found in many fungi that fight cancer function as a source of reactive oxygen species, inhibitors of mitotic kinase during cell division, and inhibitors of angiogenesis. This stops the multiplication of cancer cells and eventually kills them. Most studies agree that fungi can help in cancer treatment because they can handle many metals and store them in their bodies. This means that they can accept metals inside cells very well and bind to the cell walls very efficiently. This article discusses interesting research on fungi-mediated nanoparticles (NPs), their synthesis, and their use in cancer treatment.