ASSESSMENT OF COGNITIVE FUNCTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE

ASSESSMENT OF COGNITIVE FUNCTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE Maheshwari P

Objectives: The objectives of this study were to evaluate cognitive profile in patients with chronic kidney disease (CKD) pre-dialysis and post-dialysis, to assess the severity of cognitive impairment in patients with kidney disease before and after dialysis, and to determine the association of cognitive impairment in relation to dialysis.Methods: A total of 59 patients were recruited with CKD Stage V on dialysis for >6 months. Cognitive function of the patient was assessed by Montreal Cognitive Assessment test scale method for three intervals (before dialysis and two intervals post-dialysis), and the incidence of impairment was analyzed using one-way ANOVA variance test.Results: Among the 59 patients, there were 13 patients with the age of 18–33 years (22.033%), 11 patients with from age 34 to 49 years (18.64%), 21 patients at the age of 50–65 years (35.59%), and 15 patients around 66–80 years (25.42%). From the above categories, population with the age of 50–65 years is at maximum affected by CKD. Among the 59 patients, 24 patients (40.677%) are male and 35 patients (59.33%) are female. There was a mild significant difference seen in cognitive functioning between pre-dialysis and post-dialysis (p≤0.02).Conclusion: It was found that patients with CKD had mild-to-moderate cognitive dysfunction due to morbidities associated with CKD. Inthis study, significant differences of cognitive function result in CKD patients and the severity of cognitive impairment was associatedwith the severity of the kidney disease, which improved with dialysis. Finally, our study suggests that cognitive performance wasimproved after initiation of dialysis and that further management through medications could provide a better outcome in cognitiveperformance.
12 28 2018 10.22159/ajpcr.2018.v11s4.31734 https://innovareacademics.in/journals/index.php/ajpcr/article/view/31734 https://innovareacademics.in/journals/index.php/ajpcr/article/viewFile/31734/16648 https://innovareacademics.in/journals/index.php/ajpcr/article/viewFile/31734/16648