Synthesis, Characterization and Recyclable Cerium Loaded CuO Nanocatalyst for the Synthesis of 1, 4- Disubstituted 1, 2, 3-Triazoles and Propargylamines

Cerium loaded CuO nanoparticles (Ce-CuO NPs) were successfully synthesized by a precipitation-thermal decomposition method. The synthesized Ce-CuO NPs were used as a nanocatalyst for the synthesis of 1, 4-disubstituted-1, 2, 3-triazoles by the click reaction of substituted benzyl azides and alkynes and synthesis of propargylamines via a three-component coupling reaction of aldehydes, alkynes and amines under ultrasonication. One-pot operation, atom-economical nature, regioselectivity and good yields are the significant features of this protocol. The reusability of the prepared nanocatalyst was successfully examined six times without any appreciable loss in catalytic activity. Synthesized compounds were characterized by 1H NMR, 13C NMR and mass spectral studies.