Sources, blood concentrations, and approaches for reducing exposure to lead: A critical appraisal on lead poisoning

Amin, Ruhul and Alam, Faruk and Dey, Biplab Kumar and Darwin, Ronald and Ahmed, Shajed Ali and Thalluri, Chandrashekar and Dhama, Kuldeep and Chakraborty, Sandip and Chandran, Deepak and Mandhadi, Jithendar Reddy (2023) Sources, blood concentrations, and approaches for reducing exposure to lead: A critical appraisal on lead poisoning. Journal of Experimental Biology and Agricultural Sciences, 11 (3). pp. 506-519. ISSN 2320-8694

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Abstract

Lead, a non-essential metal, enters the body in various ways, making it a major public health issue.
Painters and smelters report lead poisoning in children and staff. Mining and battery workers risk lead exposure. Traditional and cultural remedies may include dangerous quantities of lead, producing lead poisoning. These drugs must be properly understood and regulated to avoid toxicity. Lead poisoning symptoms vary by duration and severity. Lead first impairs cognition, development, and behaviour by
damaging the neural system. Time degrades reproductive and haematological systems. Lead's quiet entry into the body makes it deadly. Acute lead nephropathy damages kidneys at 100mg/dL. Lead levels
exceeding 150mg/dL may induce encephalopathy. Blood lead levels indicate lead poisoning severity. Lead levels over 10g/dL in children and 40g/dL in adults are hazardous. Lead toxicity affects various organs. Lead may induce hypertension and cardiovascular disease. It may also cause chronic kidney disease and renal failure. Lead exposure may impede fertility, cause miscarriages, and alter foetal development; hence the reproductive system is vulnerable. Symptoms and lead levels may be treated with
different approaches. Lead chelation treatment is frequent. Other vitamins and medications may enhance

Item Type: Article
Subjects: Pharmaceutical Chemistry and Analysis > Pharmaceutical Analysis
Divisions: Pharmaceutical Chemistry and Analysis
Depositing User: Mr IR Admin
Date Deposited: 18 Sep 2024 08:58
Last Modified: 18 Sep 2024 08:58
URI: https://ir.vistas.ac.in/id/eprint/6373

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