Coumarin‐Oxazolyl‐Based Chemosensor for Selective Detection of Fe 2+ Ions: Preparation, Spectral Characterization, Theoretical Studies and Cellular Bioimaging

Coumarin‐Oxazolyl‐Based Chemosensor for Selective Detection of Fe 2+ Ions: Preparation, Spectral Characterization, Theoretical Studies and Cellular Bioimaging Giriraj Kalaiarasi Centre for Material Chemistry Karpagam Academy of Higher Education (Deemed to be University) Coimbatore 641 021 India Department of Chemistry Karpagam Academy of Higher Education (Deemed to be University) Coimbatore 641 021 India https://orcid.org/0000-0003-2712-2094 Mohanasundaram Ranjani Department of Chemistry Bharathiar University Coimbatore 641 046 India Mani Aswathy Department of Chemistry Karpagam Academy of Higher Education (Deemed to be University) Coimbatore 641 021 India Arumugam Kosiha School of Basic Sciences Vels Institute of Science Technology & Advanced Studies (Deemed to be University) Chennai 600 117 India Rathinasabapathi Prabhakaran Department of Chemistry Bharathiar University Coimbatore 641 046 India Abstract

New coumarin‐oxazolyl derived receptor ( E )‐3(2‐(2‐(1‐(2‐oxo‐2H‐chromen‐3‐yl)ethylidene)hydrazinyl)oxazol‐4‐yl)‐2 H ‐chromen‐2‐one ( AOX ) was designed, synthesised from the reaction of 3‐acetyl‐coumarin semicarbazone with 3‐bromoacetyl coumarin in chloroform/ethanol and the formation of AOX was confirmed by using different spectroscopic methods. The interaction of the AOX with different metal ions was investigated using photometric titrations and its selectively detected the Fe 2+ ions.
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