Comparative Study of Desogestrel- Containing Oral Contraceptive and Levonorgestrel- Containing Oral Contraceptive in Dysfunctional Uterine Bleeding

Dysfunctional uterine bleeding is a type of abnormal uterine bleeding where
vaginal bleeding occurs outside of the menstrual cycle in the absence of any
known pelvic pathology. Dysfunctional uterine bleeding can be treated safely

with hormone therapy. Combined oral contraceptives help in increased men-
strual cycle regularity and decreased blood loss. In this study, a reliable drug

for the dysfunctional uterine bleeding with maximum effectiveness and mini-
mal side effects were assessed. This study was conducted on 120 cases of dys-
functional uterine bleeding. Patients who were diagnosed with dysfunctional

uterine bleeding were randomly assigned into two groups. Group D and group
L included patients who were given Ethinyl estradiol 0.02mg + desogestrel0.15mg and Ethinyl estradiol 0.03mg + levonorgestrel 0.15mg respectively forthe four consecutive 28- day cycles. Menstrual blood loss was assessed usingthe pictorial blood assessment chart (PBAC) score on 2nd and 4th monthsof recruitment. Side effects such as weight gain, acne and headache wereassessed in both groups. This study shows 56.68% reduction in mean PBAC