Ceric Ammonium Nitrate supported on Hy-Zeolite Catalyzed Oxidative Condensation Reaction and its Docking Studies

Ceric Ammonium Nitrate supported on Hy-Zeolite Catalyzed Oxidative Condensation Reaction and its Docking Studies Sudha R Department of Chemistry, School of Basic Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Chennai, Tamil Nadu. Nithya G. Department of Chemistry, School of Basic Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Chennai, Tamil Nadu. Brindha Devi P Department of Bio-Engineering, B. Tech Biotechnology, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Chennai, Tamil Nadu. P. Indra Priyatharesini Department of Chemistry, School of Basic Sciences, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Chennai, Tamil Nadu.
The chemistry of chalcone has been recognized as a significant field of study. Chalcone serve as to prepare starting materials for the synthesis of various heterocyclic compounds. From the backbone of reported literature, we have developed an alternative heterogeneous and simple catalytic system for the synthesis of chalcones via the oxidative condensation of benzyl alcohol with substituted acetophenone using metal nitrate supported HY-Zeolite as a catalyst. 30 mol% CAN supported HY-zeolite has been efficiently used as a catalyst for the oxidative condensation reaction of benzyl alcohol with substituted acetophenones in the presence of hydrogen peroxide as an oxidant in toluene to afford the corresponding chalcones in good to moderate yields. Docking studies were carried out for the synthesized compounds towards the protein Lysine aminotransferase using the software. 8 6 2021 8 6 2021 4270 4274 10.52711/0974-360X.2021.00741 https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-47 10.1039/B918763B P. Anastas, N. Eghbali, Chem. Soc. Rev. 2010, 39, 301. 10.1007/s11244-009-9306-1 V. R. Choudhary, D. K. Dumbre, Top. Catal. 2009, 52, 1677. 10.1021/ja809883c M. Conte, H. Miyamura, S. Kobayashi, V. Chechik, J. Am. Chem. Soc. 2009, 131, 7189. 10.1126/science.1120560 D. I. Enache, J. K. Edwards, P. Landon, B. Solsona-Espriu, A. F. Carley, A. A. Herzing, M. Watanabe, C. J. Kiely, D. W. Knight, G. J. Hutchings, Catal. Sci. 2006, 311, 362. 10.1002/adsc.200900239 T. Mitsudome, A. Noujima, T. Mizugaki, K. Jitsukawa, K. Kaneda, Adv. Synth. Catal. 2009, 351, 1890. 10.1002/adsc.200600435 G. Palmisano, S. Yurdakal, V. Augugliaro, V. Loddo, L. Palmisano, Adv. Synth. Catal. 2007, 349, 964. N. Lingaiah, K. M. Reddy, N. Seshu Babu, K. Narasimha Rao, I. Suryanarayana, P. S. Sai Prasad, Catal. Commun. 2006, 7, 245. 10.1002/0471264180.or053.01 F. A. Luzzio, The oxidation of alcohols by modified oxochromium (VI)-Amine reagents in organic reactions, L. A. Paquette, Ed, Wiley, New York, 1998, 53, 1. 10.1007/978-3-540-75997-3_139 Z. Q. Lei, R. R. Wang, Catal. Commun. 2008, 9, 740. 10.1016/j.cclet.2007.06.007 Z. H. Weng, J. Y. Wang, X. Gao Jian, Chin. Chem. Lett. 2007, 18, 936. 10.1016/j.molcata.2004.01.009 V. R. Choudhary, D. K. Dumbre, B. S. Uphade, V. S. Narkhede, J. Mol. Catal. A. Gen. 2004, 215, 129. 10.1016/j.catcom.2008.05.008 V. Mahdavi, M. Mardani, M. Malekhosseini, Catal. Commun. 2008, 9, 2201. 10.1039/B212585B M. Musawir, P. N. Davey, G. Kelly, I. V. Kozhevnikov, Chem. Commun. 2003, 1414. 10.1021/ja01854a021 I. Adkins, R. C. Franklin, J. Am. Chem. Soc. 1941, 63, 2381. M. Metayer, S. Roumens. Campt. Rend. 1947, 496, 1324. 10.1021/jo00067a058 S. J. Wittenberger, B. G. Donner, J. Org. Chem. 1993, 58, 4139. 10.1021/jo010635w Z. P. Demko, K. B. Sharpless, J. Org. Chem. 2001, 66, 7945. 10.1002/ange.200605095 L. Bosch, J. Vilarrasa, Angew. Chem. 2007, 119, 4000. M. L. Kantam, K. B. Shiva Kumar, C. Sridhar, Adv. Synth. Catal. 2005, 347, 121., S. M. Agawane, J. M. Nagarkar, Catal. Sci. Technol. 2012. 10.1002/anie.200605095 L. Bosch, J. Vilarrasa, Angew. Chem. 2007, 46, 3926. W. F. Hoelderich, B. A. Haft, Structure-activity and selectivity relationships in heterogeneous catalysis, Elsevier, Amsterdam, 1991. 10.1016/S0024-3205(99)00120-4 G. D. Carlo, N. Mascolo, A. A. Izzo, F. Capasso, Life Sci. 1999, 65, 337. 0.22159/ajpcr.2017.v10i5.17157 Brindha Devi., Rajagopal K, Esther Elizabeth., Asian Journal of Pharmaceutical and Clinical Research, [S.l.], p. 140-146, may 2017. ISSN 2455-3891. 10.1016/j.bmcl.2011.09.011 Corradi V, Mancini M, Santucci MA, Carlomagno T, Sanfelice D, Mori M, Vignaroli G, Falchi F, Manetti F, Radi M, Botta M. Bioorg Med Chem Lett, 2011; 21: 6867–71. 10.1002/minf.201400120 Devi PB, Jogula S, Reddy AP, Saxena S, Sridevi JP, Sriram D, Yogeeswari P. 2015 Feb 1; 34(2‐3): 147-59. 10.1016/j.tube.2015.04.010 Devi PB, Sridevi JP, Kakan SS, Saxena S, Jeankumar VU, Soni V, Anantaraju HS, Yogeeswari P, Sriram D. 2015 Dec 1; 95(6): 786-94. G. Nithya., Sudha R., Brindha Devi P. Charles C Kanakam., Asian Journal of Pharmaceutical and Clinical Research, [S.l.], p. 186-189, dec. 2017. 0.1016/j.addr.2012.09.019 Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Adv Drug Delivery Rev, 2012; 64: 4–17. 10.2174/138620711795767820 Luu TT, Malcolm N, Nadassy K. Comb Chem High Throughput Screen, 2011; 14: 488–99. 10.7324/JAPS.2018.81120 Meenambiga SS, Venkataraghavan R, Biswal A. J App Pharm Sci, 2018; 8(11): 140–150. 10.1111/cbdd.12655 Parthiban BD, Saxena S, Chandran M, Jonnalagadda PS, Yadav R, Srilakshmi RR, Perumal Y, Dharmarajan S. Chemical biology & drug design. 2016 Feb; 87(2): 265-74. 10.1016/j.jmgm.2013.08.005 Saxena S, Devi PB, Soni V, Yogeeswari P, Sriram D. 2014 Feb 1; 47: 37-43.