Syntheses and characterization of Syzygium aromaticum, Elettaria cardamomum and Cinnamomum verum modified TiO2 and their biological applications

Diseases form the major roadblock for the living organism. Many chemicals are isolated to cure
diseases. But they are found to have side effects due to allergetic chemicals. NPs are found to be good
biological agents. But they are also allergetic in nature. In this study, the properties of TiO NPs were
modified with bio agents such as Clove, Elachi (Cardamom) and Cinnamon. The anticancer and
antibacterial properties were also examined. XRD analysis showed the anatase phase for the pure and
modified TiO samples. The particle sizes were found to be 7.5nm for pure, 9.5nm for Clove modified,
9nm for Elachi modified and 10.5nm for Cinnamon modified TiO NPs. The synthesized TiO
nanoparticles were tested against bacterial strains such as Escherichia coli, Klebsiella pneumoniae,Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans using agar diffusion methodfor antibacterial studies. KB Oral cancer cell line was used to determine the anticancer activities of thesynthesized NPs by MTT assay. The synthesized bio modified NPs exhibit significant results againstbacterial strains and cancer cell line when compared with the pure NPs.