Antibacterial activity of silver nanoparticles phytosynthesized from Glochidion candolleanum leaves

In the present study, Glochidion candolleanum (Wight & Arn.) Chakrab. & M. Gangop. leaf (GCL)-ethyl acetate extractwas used for the phytosynthesis of silver nanoparticles (AgNPs) and subjected to antibacterial assay with G and G bacteria. The GCL·AgNPs synthesized were characterized through various spectroscopic and microscopic analyses,while the phytochemical compounds was analyzed by GC–MS. The discrete GCL·AgNPs formed were micron-scalerange. TEM images of AgNPs reveal that nanoparticles were spherical and ellipsoidal in shape, dispersed uniformly andcapped with secondary material of ≈10 nm thickness. A maximum inhibition zone of 12.2 mm diameter was observedagainst Salmonella enterica followed by 11.8 mm diameter against Pseudomonas aeruginosa . GC–MS analysis revealedthe occurrence of bioactive phytocompounds in GCL extract, hexamethylcyclotrisiloxane, 2,4,6-cycloheptatrien,benzenepropanoic acid, 2-ethylacridine, benzo[h]quinoline, methyltris(trimethylsiloxy)silane and 5-methyl-2-phenylindolizine. The findings suggest that GCL could be used for developing antibacterial AgNPs against pathogenicbacteria.