Jambula Dinesh Babu, T and Venugopalan Santhosh Kumar, Y (2021) Studies on antioxidant activity of different extracts of aerial parts of Cadaba farinose Forsk: An in-vitro techniques. International Journal of Research in Pharmaceutical Sciences, 11 (3). pp. 2986-2992. ISSN 0975-7538
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Abstract
Cadaba farinosa (family Capparidaceae) is generally known as “Indian cadaba”
in the traditional ayurvedic system. The current study, aerial parts of differ-
ent concentrates (Pet.ether, ethyl acetate and methanol) of Cadaba farinose
was evaluated for its in-vitro antioxidant potential by Diphenylpicrylhydrazyl
radical, and total antioxidant activity taking ascorbate as standard and super-
oxide radical activity taking Quercetin as the standard for the in-vitro meth-
ods. The methanolic concentrates of Cadaba farinose& ascorbic acid exhibited
antioxidant potential possessing IC50 208μg/ml & 66μg/ml (Diphenylpicryl-
hydrazyl radical) , 188μg/ml & 57μg/ml (total antioxidant). The methanolic
concentrates of Cadaba farinose & quercetin exhibited antioxidant potential
possessing IC50 252μg/ml & 60μg/ml (superoxide radical). The IC50 value
was originated that methanolic concentrates of Cadaba farinose more efβicient
in Diphenylpicrylhydrazyl radical, superoxide radical activity, total antioxi-
dant activity compared EA & PE concentrates. The difference in scavenging
potential of the extracts can be due to variation in the percentage of bioac-
tive compound present in different solvents. Invitro antioxidant studies showmethanolic concentrates of Cadaba farinose have better antioxidant activity.
This result indicates that aerial parts of methanolic concentrate Cadaba fari-nose could serve as a natural antioxidant, which may be useful in preventingfree radical-induced diseases.
Item Type: | Article |
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Subjects: | Pharmacology > Drug Delivery Systems |
Divisions: | Pharmacology |
Depositing User: | Mr IR Admin |
Date Deposited: | 11 Sep 2024 05:11 |
Last Modified: | 11 Sep 2024 05:11 |
URI: | https://ir.vistas.ac.in/id/eprint/5495 |