Ecthyma gangrenosum-Source Reduction along with Empirical Antibiotics and Wound Care Helps to Treat Serious Infections

Ramya, A. and Raja, M. Manoj Kumar and Bhavya, E. and K, Vivekananadan (2021) Ecthyma gangrenosum-Source Reduction along with Empirical Antibiotics and Wound Care Helps to Treat Serious Infections. Journal of Pharmacology and Pharmacotherapeutics, 11 (1). pp. 30-32. ISSN 0976-500X

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Abstract

Ecthyma gangrenosum (Eg) is a cutaneous necrotic lesion that is mostly seen in immunocompromised patients. It reflects a severe sepsis,
possibly caused by Pseudomonas aeruginosa, an aerobic Gram-negative opportunistic pathogen that has a high risk of associated mortality in
cases where the infection is systemic. These skin lesions may be seen on admission or can develop later. The recognition of Eg lesions permits
the earliest possible introduction of the most effective antimicrobial therapy, which is a key prognostic factor for survival. A 52‐year‐old male
patient admitted to the surgery department presented a sepsis associated green color pus discharge with pain and swelling. An empiric antibiotic
therapy was prescribed. Five days after admission, pus culture was positive for Pseudomonas aeruginosa. As a result, the decision was madeto continue the antibiotic therapy. Empiric therapy leads to granulation tissue formation. Eg can be treated with simple antibiotic therapy.

Item Type: Article
Subjects: Pharmaceutics > Pharmaceutical Microbiology
Divisions: Pharmaceutics
Depositing User: Mr IR Admin
Date Deposited: 11 Sep 2024 04:31
Last Modified: 11 Sep 2024 04:31
URI: https://ir.vistas.ac.in/id/eprint/5490

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