Drug Bioavailability, Stability and Anticancer Effect of Berberine-loaded Magnetic Nanoparticles on MDA-MB-231 Cells in Breast Cancer

Breast cancer is the most causative factors of death in women. Treatment often consists of surgery, radiation therapy, and chemotherapy, have several side effects. Berberine is an alkaloid naturally-derived from Berberis aristata and a family Berberidaceae exhibits a broad spectrum of pharmacological benefits, including antiviral
and anticancer properties etc. The recent development of nanomedicine is an art of delivering drugs to the target-site by improving their safety and efficacy. Among them,
Magnetic nanoparticles play a key role to show their targeted drug delivery using a magnetic field.