Pilli, Gayathri Devi and Elumalai, Karthikeyan and Muthukumar, Vijey Aanandhi and Sundaram, Palani Shanmuga (2022) A revised analysis of current and emerging Nano suspension technological approaches for cardiovascular medicine. Beni-Suef University Journal of Basic and Applied Sciences, 11 (1). ISSN 2314-8543
![[thumbnail of 20.pdf]](https://ir.vistas.ac.in/style/images/fileicons/archive.png)
20.pdf
Download (1MB)
Abstract
A revised analysis of current and emerging Nano suspension technological approaches for cardiovascular medicine Gayathri Devi Pilli Karthikeyan Elumalai http://orcid.org/0000-0002-6259-5332 Vijey Aanandhi Muthukumar Palani Shanmuga Sundaram Abstract Background
This is an objective critique to give an in-depth description of Nano suspensions. This article is attempting to address the issue of whether or not Nano science is realistic with respect to price, with regards to item costs being added to the endeavor and Lipotropic drugs have proven to be rewarding and Lipo-immunotherapy has proven to be beneficial. In modern times, drug marketing and promotion have become crucial to efficient commercializing of successful molecules, pharmaceutical companies often work to increase the chances of promoting successful drugs, these included cardiovascular drugs because of their widespread usage.
Main body
Nano suspension is a Nano metric Colloidal Suspension system i.e., Nano suspensions, in the solid form reaches the bloodstream and Nanoparticle colloids readily available to the target cells. All research on Nanostructures is focused on the four primary dimensions, composition, homogeneity, heterogeneity, elasticity, and agglomeration. Researchers are devising ways to deliver medication and other substances to a damaged cell and diseased region, as well as diagnose the body to pinpoint disease and defects, by way of Nanotechnology.
Short conclusions
The vital analysis of Nano science experiment on Nano suspension is working to achieve the goal of reducing product cost by using Nanotechnology in product development, as it wants to examine the probability of development by utilizing Nanotechnology. The usage of the top-limited technology allows the development of cardiovascular drugs classified under the biopharmaceutical classification system (Class II and Class IV) to use two approaches namely top-down and bottom-up methods.
01 15 2022 12 2022 10 193 1 10.1007/springer_crossmark_policy link.springer.com false 26 July 2021 4 January 2022 15 January 2022 Not applicable. Not applicable. The authors declare no competing interest in this study. https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 10.1186/s43088-022-00193-4 20220115130225824 https://bjbas.springeropen.com/articles/10.1186/s43088-022-00193-4 https://link.springer.com/content/pdf/10.1186/s43088-022-00193-4.pdf https://link.springer.com/content/pdf/10.1186/s43088-022-00193-4.pdf https://link.springer.com/article/10.1186/s43088-022-00193-4/fulltext.html J Nanomater Y Roya 2015 1 2015 10.1155/2015/761517 Roya Y, Krasimir V, Spomenka S (2015) Nanosuspension technologies for delivery of poorly soluble drugs. J Nanomater 2015:1–13 J Nanobiotechnol KP Jayanta 71 1 2018 Jayanta KP, Gitishree D, Leonardo FF, Estefania VRC, Maria PRT et al (2018) Nano based drug delivery system: recent developments and future prospects. J Nanobiotechnol 71:1–33 Int J Curr Pharm Res SA Smita 9 19 2017 Smita SA, Sagar TM, Saudagar RB (2017) Review article Nanosuspension an overview. Int J Curr Pharm Res 9:19–23 Nano Nanotechnol Res SP Sachin 4 2 59 2017 Sachin SP, Bajirao RD, Sandip PN, Rajan SS (2017) Nanosuspension technologies for delivery of drugs. Nano Nanotechnol Res 4(2):59–66 J Pharm Res SP Chaudhari 3 2 241 2010 Chaudhari SP, Kamble SC, Mahajan RA, Jagdale S, Ratnaparkhi MP (2010) Nanosuspension: a novel drug delivery system. J Pharm Res 3(2):241–246 In J Curr Pharm Rev Res P Mitesh 3 4 96 2011 Mitesh P, Arpit S, Patel NM, Patel MR, Patel KR (2011) Nanosuspension: a recent approach for nano drug delivery system. In J Curr Pharm Rev Res 3(4):96–101 Int J Bas Clin Pharm S Diana 6 12 2766 2017 10.18203/2319-2003.ijbcp20175200 Diana S, Debora F, Joana LR, Lígia RR (2017) Nanotechnology: a revolution in targeted drug delivery. Int J Bas Clin Pharm 6(12):2766–2773 Int Res Pharm BS Girish 2 2 40 2011 Girish BS, Rakesh PP, Prajapati BG, Nikunjana AP (2011) Solid lipid nanoparticles and nano lipid carriers: as novel solid lipid based drug carrier. Int Res Pharm 2(2):40–52 Int J Pharm Sci S Mukerjee 71 4 349 2009 Mukerjee S, Ray S, Thakur RS (2009) Solid lipid nanoparticles: a modern formulation approach in drug delivery system. Int J Pharm Sci 71(4):349–358 10.1016/B978-0-12-813351-4.00023-7 Menaka J (2018) Current trends in industrial scale synthesis of quantum dots and its application in electronics. In Handbook of nanomaterials for industrial applications, pp 381–385 Am J Neuroradiol G Suffredini 35 7 2013 10.3174/ajnr.A3543 Suffredini G, East JE, Levy LM (2013) Studied a new applications of nanotechnology for neuroimaging citied in March 2013. Am J Neuroradiol 35:7. https://doi.org/10.3174/ajnr.A3543 J Nano Technol IMV Aura 2012 1 2012 Aura IMV, Teresa GQ, Rosa ENA, Laura-SAT VC (2012) Polymeric and ceramic nanoparticles in biomedical applications. J Nano Technol 2012:1–10 J Drug Target ISF Asif 20 813 2012 10.3109/1061186X.2012.716845 Asif ISF, Jasjeet KS, Sanjula B, Shweta D, Javed A (2012) Nanostructured lipid carriers system: recent advances in drug delivery. J Drug Target 20:813–830 Nat Rev Drug Dis Rev E Iriny 18 273 2019 10.1038/s41573-018-0005-0 Iriny E, Colson Y, Grinstaff M (2019) Polymer-drug conjugate therapeutics: advances, insights and prospects uses. Nat Rev Drug Dis Rev 18:273–294 Int J Poly Mater Poly Biol LG Monika 69 990 2020 10.1080/00914037.2019.1655745 Monika LG, Priyanka GP, Pradum PI (2020) Polymer-drug conjugates as nanomedicine: a review. Int J Poly Mater Poly Biol 69:990–1014 Int J Poly Matrt Poly Biol KM Ardhendu 70 4 287 2021 10.1080/00914037.2020.1713780 Ardhendu KM (2021) Dendrimers in targeted drug delivery applications: a review of diseases and cancer. Int J Poly Matrt Poly Biol 70(4):287–297 Nanotechnology W Kai 30 50 502003 2019 10.1088/1361-6528/ab4241 Kai W, Diqing S, Jinming L, Renata S, Wang JP (2019) Magnetic nanoparticles in nanomedicine: a review of recent advances. Nanotechnology 30(50):502003 J Nanotechnol G Ting 2018 1 2018 Ting G, Junxing H, Chenglin Z, Weizhong T, Hong Y, Xingmao J, Jun Y, Yujuan S, Yanhong X, Xuefeng B, Xiaoqian F (2018) The recent advances of magnetic nanoparticles in medicine. J Nanotechnol 2018:1–8 J of Car Res R Gul 5 1 1 2019 Gul R, Zainab N, Asad M, Salma B, Anwar HAS, Shabeer AM, Ghulam A (2019) An overview of the recent progress in the synthesis and applications of carbon nanotubes. J of Car Res 5(1):1–31 Int Nat Nanotechnol W Yong 6 668 2011 10.1038/nnano.2011.147 Yong W, Dali Z, Qiulin T, Michal XW, Li-Qun G (2011) Nanopore-based detection of circulating microRNAs in lung cancer patients. Int Nat Nanotechnol 6:668–674 Sci Direct S Azadeh 6 131 2020 Azadeh S, Hashemi ASMGJMM (2020) Laser-assisted cancer treatment, in bio-engineering approaches to cancer diagnosis and treatment. Sci Direct 6:131–156 J Appl Phys AA Dubrovskiy 118 213901 2015 10.1063/1.4936838 Dubrovskiy AA, Balaev DA, Shaykhutdinov KA, Bayukov OA, Pletnev ON, Yakushkin SS, Bukhtiyarova GA, Martyanov ON (2015) Size effects in the magnetic properties of e-Fe2O3 nanoparticles. J Appl Phys 118:213901–213917 Int J Res Ayurveda Pharm AP Patel 2 2 448 2011 Patel AP, Patel JK, Patel K, Deshmukh AB, Mishra BR (2011) A review on drug nanocrystals a carrier free drug delivery. Int J Res Ayurveda Pharm 2(2):448–458 Nanomedicine KE Boubbou 13 953 2018 10.2217/nnm-2017-0336 Boubbou KE (2018) Magnetic iron oxide nanoparticles as drug carriers: clinical relevance. Nanomedicine 13:953–971 J Occup Med Toxicol SS Sarabjeet 2 16 2007 10.1186/1745-6673-2-16 Sarabjeet SS, Hicham F, Baljit S (2007) Nanotechnology-based drug delivery systems. J Occup Med Toxicol 2:16 Int J Pharm Sci D Sneha 10 6 90 2018 Sneha D, Srinivas B, Rajashree H (2018) Preparation and characterization of oral nanosuspension loaded with curcumin. Int J Pharm Sci 10(6):90–95 J Pharm Pharmacol VB Patravale 56 7 827 2004 10.1211/0022357023691 Patravale VB, Abhijit AD, Kulkarni RM (2004) Nanosuspension: a promising drug delivery strategy. J Pharm Pharmacol 56(7):827–840 Nanosci Nanotechnol Res SP Sachin 4 2 59 2017 Sachin SP, Bajirao RD, Sandip PN, Rajan SS (2017) Nanosuspension technology in drug delivery system. Nanosci Nanotechnol Res 4(2):59–66 Md. Saddam Hussain, Abdul Baquee Ahmed And Jiban Debnath (2020) Nanosuspension: A Promising Drug Delivery System For Poorly Water Soluble Drug And Enhanced Bioavailability. IJSPR (2020), Volume 11, Issue 10. Appl Sci Manuf H Zhao 39 602 2008 10.1016/j.compositesa.2007.07.006 Zhao H, Li R (2008) Effect of water absorption on the mechanical and dielectric properties of nano-alumina filled epoxy nanocomposites, composites Part A. Appl Sci Manuf 39:602–611 Int J Pharm Pharmaceut Sci P Lakshmi 2 4 3540 2010 Lakshmi P, Kumar GA (2010) Studied a nanosuspension technology: a review citied in september 2010. Int J Pharm Pharmaceut Sci 2(4):3540 Der Pharm Let T Venkatesha 3 2 203 2011 Venkatesha T, Rajesh C, Sekar M, Jeevanandham S, Reza KH, Nagi Reddy BKV (2011) Nanosuspension: ideal approach for the drug delivery of poorly water soluble drugs. Der Pharm Let 3(2):203–213 J Drug Deliv Therap A Stanekzai 9 2 574 2019 10.22270/jddt.v9i2.2436 Stanekzai A, Vikrant SCK, Pankaj K (2019) Nanosuspension as a promising approach to enhance bioavailability of poorly soluble drugs: an update. J Drug Deliv Therap 9(2):574–582 Ind Drug KPR Chowdary 42 9 557 2005 Chowdary KPR, Madhavi BLR (2005) Novel drug delivery technologies for insoluble drugs. Ind Drug 42(9):557–563 Eur J Pharm Biol MK Cornelia 62 1 3 2006 10.1016/j.ejpb.2005.05.009 Cornelia MK, Rainer H (2006) Drug nanocrystals of poorly soluble drugs produced high-pressure homogenizations. Eur J Pharm Biol 62(1):3–16 Int J Pharm KP Krause 196 2 169 2000 10.1016/S0378-5173(99)00414-7 Krause KP, Kayser O, Mader K, Gust R, Muller RH (2000) Heavy metal intamination of nanosuspensions produced by highpressure homogenizations. Int J Pharm 196(2):169–172 Toxicol Pathol MML Elaine 6 1 43 2008 Elaine MML, Gary GL (2008) Drug nanoparticles: formulating poorly water-soluble compounds. Toxicol Pathol 6(1):43–48 J Nan Res H Desmond 12 1743 2010 10.1007/s11051-009-9759-y Desmond H, Keiko O, David JC, Chan HK, Raper JA, Ye L, Yun J (2010) Pure drug nanoparticles in tablets: what are the dissolution limitations. J Nan Res 12:1743–1754 Fu Process Technol D Jain 91 1015 2010 10.1016/j.fuproc.2010.02.021 Jain D, Khatri C, Rani A (2010) Fly ash supported calcium oxide as recyclable solid base catalyst for Knoevenagel condensation reaction. Fu Process Technol 91:1015–1021 Eur J Pharm Sci P Irene 27 299 2006 10.1016/j.ejps.2005.11.007 Irene P, Ruggero B, Ferdinando G (2006) Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics. Eur J Pharm Sci 27:299–310 Int J Pharm Technol Res KN Arun 1 1725 2009 Arun KN, Deecaraman M, Rani C, Mohanraj KP (2009) Preparation and solid state characterization of atorvastatin nanosuspensions for enhanced solubility and dissolution. Int J Pharm Technol Res 1:1725–1730 Res J Pharm Technol NN Chauhan 5 8 999 2012 Chauhan NN, Niraj VP, Suthar SJ, Jayvadan KP, Manish PP (2012) Micronization of BCS class–II drugs by various approaches for solubility enhancement—a review. Res J Pharm Technol 5(8):999–1005 Int J Pharm W Li 408 157 2011 10.1016/j.ijpharm.2011.01.059 Li W, Yang Y, Tian Y, Xu X, Chen Y (2011) Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. Int J Pharm 408:157–162 Int J Pharm Sci Nanotechnol P Jorvekar 4 1575 2012 Jorvekar P, Pathak AA, Chaudhari PD (2012) Formulation development of aceclofenac loaded nanosuspension by three square (32) factorial design. Int J Pharm Sci Nanotechnol 4:1575–1582 Int J Pharm Sci Res H Banavath 2 2 81 2011 Banavath H, Sivarama RK, Tahir A, Sajid A, Pattnaik G (2011) Nanosuspension: an approach to enhance solubility of drugs. Int J Pharm Sci Res 2(2):81–87 Int J Pharm R Shegokar 399 129 2010 10.1016/j.ijpharm.2010.07.044 Shegokar R, Müller RH (2010) Nanocrystals: industrially feasible multifunctional formulation technology for poorly soluble actives. Int J Pharm 399:129–139 Bio Technol K Srilatha 119 306 2012 10.1016/j.biortech.2012.04.098 Srilatha K, Prabhavathi DB, Lingaiah N, Prasad R, Sai PP (2012) Bio-diesel production from used cooking oil by two-step heterogeneous catalyzed process. Bio Technol 119:306–311 Int J Pharm Pharm Sci L Prasanna 2 4 35 2010 Prasanna L, Kumar G (2010) Nanosuspension technology: a review. Int J Pharm Pharm Sci 2(4):35–40 Curr Nano P Xiaohui 5 417 2009 10.2174/157341309789378177 Xiaohui P, Jin S, Mo L, Zhonggui H (2009) Formulation of nanosuspensions as a new approach for the delivery of poorly soluble drugs. Curr Nano 5:417–427 Int J Res Pharm Biomed Sci S Mohanty 1 2 41 2009 Mohanty S, Boga PK (2009) Role of nanoparticles in drug delivery system. Int J Res Pharm Biomed Sci 1(2):41–66 World J Pharmacol P Ashaben 2 2 47 2013 10.5497/wjp.v2.i2.47 Ashaben P, Kishore C, Vibhuti A, Ashim KM (2013) Ocular drug delivery systems: an overview. World J Pharmacol 2(2):47–64 J Pharm Res LM Ensign 5 3 1548 2012 Ensign LM, Cone R (2012) Nanosuspensions: potent vehicles for drug delivery and bioavailability enhancement of lipophilic drugs. J Pharm Res 5(3):1548–1554 Drug Deliv Syst A Gupta 12 1 50 2012 Gupta A, Goyal S (2012) Nanosuspension—a novel approaches. Drug Deliv Syst 12(1):50–64 Int J Pharm Biol Sci C Prabhakar 2 549 2011 Prabhakar C, Bala KK (2011) A review on nanosuspensions in drug delivery. Int J Pharm Biol Sci 2:549–558 Mater Res Bull A Sainia 93 373 2017 10.1016/j.materresbull.2017.04.011 Sainia A, Jata S, Shekhawat D, Kumar A, Dhayala V, Agarwal D (2017) Oxime-modified aluminium(III) alkoxides: potential precursors for gamma-alumina nano-powders and optically transparent alumina film. Mater Res Bull 93:373–380 Nan Struct Nano Object R Belekar 16 322 2018 10.1016/j.nanoso.2018.09.007 Belekar R, Dhoble S (2018) Activated alumina granules with nanoscale porosity for water defluoridation. Nan Struct Nano Object 16:322–328 J Pharm Sci Technol SS Satya 5 78 2015 Satya SS, Chandu BR, Ashis KM (2015) Formulation development and optimization of nanosuspension of simvastatin for improved solubility by nanomilling. J Pharm Sci Technol 5:78–87 Mater Lett B Xu 228 104 2018 10.1016/j.matlet.2018.05.135 Xu B, Wang L, Liu Y, Zhu H, Wang Q (2018) Preparation of high strength and transparent nanocomposite hydrogels using alumina nanoparticles as cross-linking agents. Mater Lett 228:104–107 Der Pharm Lett T Kiran 7 3 71 2015 Kiran T, Chintha S, Jithan A (2015) Formulation, optimization and evaluation of oral nanosuspension tablets of nebivolol hydrochloride for enhancement of dissoluton rate. Der Pharm Lett 7(3):71–84 Int J Pharm Sci Rev Res J Sandhya 24 1 177 2014 Sandhya J, Pavani A, Raja RR (2014) Formulation and evaluation of nanosuspension of nisoldipine. Int J Pharm Sci Rev Res 24(1):177–181
Item Type: | Article |
---|---|
Subjects: | Pharmaceutical Chemistry and Analysis > Pharmaceutical Validation |
Divisions: | Pharmaceutical Chemistry and Analysis |
Depositing User: | Mr IR Admin |
Date Deposited: | 09 Sep 2024 10:42 |
Last Modified: | 09 Sep 2024 10:42 |
URI: | https://ir.vistas.ac.in/id/eprint/5343 |