Green Synthesis of Selenium Nanoparticle from Medicinal Plant Extract and its Potential in The Treatment of Lung Cancer

Lung cancer is the leading cause of death globally with an estimated 238,340
people in 2023. Mukia madrespatana, a plant with ethnomedicinal properties,
exhibits numerous therapeutic effects in traditional medicine. In recent years
there has been a growing interest in utilizing selenium nanoparticles
synthesized by green mediated approach involving the plant for treating
various types of cancer. Despite notable advancements made in the past
decade there are still inherent challenges associated with these treatment
approaches. Notably, recent investigations have unveiled promising prospects
in the realm of lung cancer treatment through the discovery of antitumor
drugs derived from selenium, a trace element. Selenium nanoparticles can
serve as a viable option for drug delivery systems, facilitating the precise
control of protein kinase activity and they have been found to exhibit
regulatory effects on immunity and have shown promise in enhancing
immunotherapy for lung cancer.