An Indian Traditional Medicinal Plant For Nutraceutical Properties Of Hydroalcoholic Extract Of Solanum Torvum Fruit Coat

Objective: To study the effect of the Hydroalcoholic extract(HAE) of Solanum torvum(S.T.) fruit coat by various invitro
methods for studying its nutraceutical properties to find new, non-toxic, cost-effective and non-resistant drugs.
Methods: The fruit coat was extracted in ethanol(organic solvent) and water. This study determined phytochemical
constituents, antioxidants properties, anti-diabetic properties, anti-inflammatory properties, anti-bacterial
properties, TLC analysis, FTIR analysis and GC-MS analysis.
Results: By qualitative and quantitative phytochemical analysis, the HAE of the S.T. fruit coat showed the presence
of phenolic compounds, flavonoid and alkaloid compounds majorly, along with, carbohydrates, and saponins
compounds minorly. The antioxidant activity ofthe extract possesses the strongest in DPPH; ABTS; FRAPand in
Phosphomolybdate assay. The anti-diabetic activity showed the extract can effectively inhibit the α-amylase activity
and α-Glucosidases activity. The anti-inflammatory activity by Inhibition of Egg Albumin denaturation and by
Inhibition of the BSA denaturation. The antibacterial activity of the extract was tested against Pseudomonas aureus
and Bacillus subtilis. TLC chromatogram revealed the presence of Phenolic, Flavanoids and Alkaloids in the
extract. FTIR analysis revealed that even though almost similar bands were observed in the spectrum of both solid
and liquid medium of HAE of S.Tof fruit coat, the transmittance intensity originating from liquid form HAE of
S.T.was lower than the solid form. GC-MS analysis showed the presence of 24 compounds.
Conclusion: The study suggested that the hydroalcoholic extract of S.Tfruit coat is promising for the development in
the treatment of various human disorders in the future.