Nanoparticles for targeting brain via intranasal delivery

Barrier between the blood and brain tissue, the blood-brain barrier (BBB) has distinct properties that make
medicine distribution to the brain difficult. In order to reach the brain and hit the right spot anatomically,
we need to figure out how to get across the BBB. Nanomedicine has considerable promise for resolving this
issue, since it allows for the modification of nanoparticles with tactical molecules that can interact with
the BBB and drive absorption via the brain endothelial cells. This article discusses the feasibility of
employing nanomedicines with BBB-crossing nanoparticles to treat neurological disorders. It is difficult to
pharmacologically treat central nervous system illnesses because of the blood-brain barrier's (BBB) capacity
to block medication entrance into the brain. The advent of nanotechnology offers hope for a solution to
this issue. The BBB, the blood-brain tumor barrier (BBTB), and the nose-to-brain barrier (N2B) are only
some of the obstacles to brain-targeted medicine delivery that are discussed in this article.