A review on analytical aspects of ethosuximide: An antiepileptic drug

Patan, Afroz and Archana, M. and Poojah, A. (2023) A review on analytical aspects of ethosuximide: An antiepileptic drug. Annals of Phytomedicine An International Journal, 12 (2). ISSN 22789839

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Abstract

One out of 50 individuals can have multiple epileptic convulsions during their life, necessitating the use
of antiepileptic medication for treatment. One of the most common illnesses of the brain is epilepsy.
Ethosuximide, also known as 2-ethyl-2-methylsuccinimide, is a commonly employed succinimide for the
management of seizures known as "petit mal seizures." It is also a useful substance for research on absence
seizures. When it comes to treating kids suffering from petit mal (generalized absence) epileptic seizures,
this medication is the best option, whether used alone or in combination. Ethosuximide's main mode of
action towards absence seizures is its inhibition of low-threshold T-type (Transient-type) calcium electrical
currents within thalamic nerve cells. At the beginning of ethosuximide therapy, nausea, abdominal pain,
vomiting, diarrhea, and anorexia are frequently experienced side effects. This article provides a complete
review of the "antiepileptic drug ethosuximide” which will be helpful for the researchers for their research
purposes.

Item Type: Article
Subjects: Pharmaceutical Chemistry and Analysis > Pharmaceutical Analysis
Domains: Pharmaceutical Chemistry and Analysis
Depositing User: Mr IR Admin
Date Deposited: 28 Aug 2025 07:40
Last Modified: 28 Aug 2025 07:40
URI: https://ir.vistas.ac.in/id/eprint/10653

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