Characterization and In Vitro Antioxidative Potential of Silver Nanoparticles Biosynthesized From Annona muricata Bark

Characterization and In Vitro Antioxidative Potential of Silver Nanoparticles Biosynthesized From Annona muricata Bark S. Sudhashini Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies Pallavaram, Chennai 600117, Tamil Nadu, India https://orcid.org/0009-0007-4906-8793 P. Amudha Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies Pallavaram, Chennai 600117, Tamil Nadu, India https://orcid.org/0000-0001-6828-9558 J. Manjunathan Department of Biotechnology, School of Life Sciences, Vels Institute of Science Technology and Advanced Studies (VISTAS), Pallavaram, Chennai 600117, Tamil Nadu, India https://orcid.org/0000-0002-5745-0278 R. Vidya Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies Pallavaram, Chennai 600117, Tamil Nadu, India https://orcid.org/0000-0001-8256-9847 R. Satheesh Kumar Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies Pallavaram, Chennai 600117, Tamil Nadu, India https://orcid.org/0009-0005-0869-0776 Ambiga Somasundaram Department of Biochemistry, School of Arts and Science, Ponnaiyah Ramajayam Institute of Science and Technology (PRIST), Thanjavur 613403, Tamil Nadu, India https://orcid.org/0000-0002-2863-8618 Pasiyappazham Ramasamy Department of Prosthodontics and Implantology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, Tamil Nadu, India Polymer Research Laboratory (PR Lab), Centre for Marine and Aquatic Research (CMAR), Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 602105, Tamil Nadu, India https://orcid.org/0000-0003-0099-2102

This study introduces a highly effective technique for producing silver nanoparticles (AgNPs) utilizing an extract from the bark of Annona muricata, which is rich in bioactive compounds. The AgNP synthesis was performed at room temperature, providing an environment-friendly and cost-effective alternative to traditional methods that involve harmful chemicals and high energy consumption. Characterization of the AgNPs was performed using various techniques: scanning electron microscope and transmission electron microscope analyses revealed spherical nanoparticles ranging from 29[Formula: see text]nm to 67[Formula: see text]nm in size, FTIR techniques was used to analyze the functional groups involved in the reduction and stabilization, UV-Vis spectroscopy confirmed surface plasmon resonance peaks, X-ray diffraction analysis indicated a face-centered cubic crystal structure and energy-dispersive X-ray (EDAX) analysis verified the elemental composition and stabilization. The antioxidant properties of biogenic AgNPs were evaluated using in vitro assays, which demonstrated their significant antioxidant efficacy. This study highlights the potential of A. muricata bark extract as a sustainable and effective agent for decreasing and stabilizing the synthesis of AgNPs. This technique demonstrates promising potential as antioxidant therapy.
03 25 2025 2550046 10.1142/S1793292025500468 10.1142/S1793292025500468 https://www.worldscientific.com/doi/10.1142/S1793292025500468 https://www.worldscientific.com/doi/pdf/10.1142/S1793292025500468