ADVANCES IN NOVEL DRUG DELIVERY SYSTEMS: MECHANISMS, APPLICATIONS AND COMMERCIAL ASPECTS

The novel drug delivery system is an advanced technology or formulation approach
designed to transport pharmaceutical compounds into the body more safely and
effectively than conventional methods (like tablets or injections). Key goals include
controlling the rate of release, improving drug targeting to specific tissues, and
enhancing bioavailability. The performance of an existing medicinal molecule in
terms of patient compliance, safety, and efficacy can be greatly enhanced by
evolving it from a traditional form to a unique delivery mechanism. An old
medication molecule can be given new life as a novel drug delivery system. The
limitations of the conventional drug delivery methods are addressed by the
innovative drug delivery system, which is a novel method of drug administration.
A significant improvement in the ability to release a drug at a specified spot and
rate is possible with a novel drug delivery system that is properly developed.
Pharmaceutical companies are working to create novel drug delivery systems in
order to give medications to patients effectively and with fewer side effects. NDDS
include carrier-based systems such as liposomes, nanoparticles, microspheres,
niosomes, solid lipid nanoparticles, and polymeric systems, as well as non-carrierbased approaches. The integration of nanotechnology and controlled-release
strategies has significantly enhanced therapeutic efficacy while reducing toxicity
and side effects. This review highlights the principles, advantages, disadvantages,
approaches, and applications of novel drug delivery systems, emphasizing their
role in modern pharmaceutical research and future therapeutic development.