Facile Synthesis Of Cnps From Mesosphaerum Sauveolens And Its Antimicrobial, Antioxidant And Anticancer Property
Priyanka, S and Sanjeev Kumar, R and Vardhana, J and Kannan, KP and Bhuvaneswari, S and Udaya Prakash, NK (2025) Facile Synthesis Of Cnps From Mesosphaerum Sauveolens And Its Antimicrobial, Antioxidant And Anticancer Property. International Journal of Environmental Sciences, 11 (16). pp. 642-649. ISSN 2229-7359
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Abstract
Carbon nanoparticles are widely used in biological application due to their biocompatibility. However, the characters
of CNPs depends upon the method of synthesis and origin of the material. In this study, CNPs are synthesized from
an aromatic, medicinal plant Mesosphaerum sauveolens through open incineration method in the form of biosoot.
The biosoot thus collected were characterized for their nanoproperties using DLS, SEM, XRD, FTIR and BET.
Further their biological activities like antimicrobial property were evaluated using few bacteria and fungal species.
The antioxidant property of the CNPs of Mesosphaerum saueolens was evaluated using DPPH free radical. The
anticancer ability was evaluated against the breast cancer cell line MFC-7. The study revealed the size of the biosoot
of Mesosphaerum sauveolens falls between 121 to 289nm; 344nm to 818nm and 2313nm to 5500nm when studied
through DLS, SEM revealed the size range between 30 to 50nm, The XRD revealed the nature of CNPs as both
crystalline and amorphous in nature. FTIR revealed the presence of alkynes, Phosphines, Alkyl mercaptans, Aromatic
hydrocarbon and secondary amines as its associated compounds. BET revealed the total pore volume as 2.5388
02cc/gm and the mean pore size as 0.8nm. The antimicrobial study revealed that CNPs of Mesosphaerum sauveolens
controlled all the bacteria studied except that of Pseudomonas aeruginosa and between the fungi, Aspergilus flavus
was controlled when compared to Aspergillus niger. The EC50 value recorded for DPPH was at 32µg. The LD50
dosage for anticancer actvity against the breast cancer cell line recorded was 69.77µg. The study revealed the easiest
method to synthesis CNPs from the medicinal plant. The synthesized CNPs of Mesosphaerum sauveolens can act as
a potential antimicrobial, antioxidant and anticancer agent after proper study for their toxicity. These CNPs of
Mesosphaerum sauveolens can be successfully used in cosmetic and pharmaceutical industry as an amendment to
topical creams.
| Item Type: | Article |
|---|---|
| Subjects: | Biotechnology > Nanotechnology |
| Domains: | Biotechnology |
| Depositing User: | user 12 12 |
| Date Deposited: | 21 May 2026 09:12 |
| Last Modified: | 21 May 2026 09:12 |
| URI: | https://ir.vistas.ac.in/id/eprint/20524 |

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