Recent Advancement for the Management of COPD Disorders

Chronic Obstructive Pulmonary Disease (COPD) is a progressive
respiratory disorder affecting more than 390 million individuals
worldwide, accounting for approximately 3.2 million deaths annually.
Recent advancements in COPD management focus on precision
pharmacotherapy, digital health technologies, regenerative medicine,
and sustainable healthcare delivery models. This chapter presents a
comprehensive evaluation of contemporary COPD management
strategies, integrating quantitative clinical outcomes such as forced
expiratory volume in one second (FEV₁) improvement of 8–15%, 30–
45% reduction in acute exacerbation rates, and 20–35%
enhancement in patient-reported quality-of-life indices. Emphasis is
placed on novel inhaled drug delivery systems, biologics, artificial
intelligence–assisted diagnostics, telemedicine-based monitoring,
and sustainability-driven healthcare innovations. The chapter aligns
these advancements with Sustainable Development Goals (SDGs 3,
Dr. K. Arumuganainar, Mrs. Dimple Juneja, Dr. M. Karthick, Dr. S. Vishnu
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9, and 12) and evaluates their Technology Readiness Levels (TRLs 4–
9), offering a translational pathway from laboratory research to
clinical implementation.
Keywords: Chronic obstructive pulmonary disease, Precision
medicine, Digital health, Sustainable healthcare, advanced drug
delivery