Development and Multivariate Optimization of a Stability-Indicating UHPLC-Qtof-MS Method for Simultaneous Quantification of Structurally Related Impurities in a Novel Antineoplastic Drug under Accelerated Stress Conditions

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Malarkodi, Velraj (2025) Development and Multivariate Optimization of a Stability-Indicating UHPLC-Qtof-MS Method for Simultaneous Quantification of Structurally Related Impurities in a Novel Antineoplastic Drug under Accelerated Stress Conditions. Development and Multivariate Optimization of a Stability-Indicating UHPLC-Qtof-MS Method for Simultaneous Quantification of Structurally Related Impurities in a Novel Antineoplastic Drug under Accelerated Stress Conditions, 43. ISSN 1003-2053

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Abstract

Comprehensive impurity profiling and stability evaluation are critical for ensuring the safety, efficacy, and regulatory compliance of novel antineoplastic agents. Apoptinib, a newly developed targeted anticancer drug, possesses structural features that render it susceptible to chemical degradation, necessitating the development of a robust stability-indicating analytical method.

Item Type:	Article
Subjects:	Pharmacognosy > Phytochemistry
Domains:	Pharmacognosy
Depositing User:	Mr IR Admin
Date Deposited:	12 May 2026 14:26
Last Modified:	12 May 2026 14:26
URI:	https://ir.vistas.ac.in/id/eprint/19062

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