RECENT ADVANCES IN MOUTH DISSOLVING TABLET TECHNOLOGY: A REVIEW OF FORMULATION, EVALUATION, AND INNOVATIONS

Mouth dissolving tablets (MDTs), also called Orally Disintegrating Tablets, are a useful type of oral dosage form that dissolves quickly in the mouth without water. They are particularly helpful for children, elderly patients, and anyone who has trouble swallowing regular tablets.
This review highlights the different ways MDTs are made, their quality evaluation, and recent improvements in their technology. Common methods of preparation include direct
compression, freeze-drying, sublimation, and spray drying, which help tablets disintegrate fast and deliver drugs effectively. Quality checks such as disintegration time, hardness, friability, and drug release studies are important to ensure their performance. Recently, advances like better superdisintegrants, taste-masking strategies, and modern manufacturing techniques have improved their efficiency and patient acceptability. Overall, MDTs provide a simple, convenient, and patient-friendly approach in modern drug delivery systems.