Advancements in nanostructured drug delivery systems: Innovations in targeted therapy and multifunctional nanomaterials

Pavithran, Kumar and Manjunathan, Jagadeesan (2025) Advancements in nanostructured drug delivery systems: Innovations in targeted therapy and multifunctional nanomaterials. Next Nanotechnology, 9: 100381. ISSN 2949-8295

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Abstract

Recent advancements in nanotechnology have highlighted the potential of nanoparticles in medical applications.
This is especially true for targeted drug delivery systems. Nanoparticles offer unique characteristics, such as
stable ligand interactions, varied sizes and shapes, and high carrier capacities. These features make them ideal for
carrying both hydrophilic and hydrophobic substances in disease therapy. Novel therapeutic nanostructures have
shown promise in targeted drug delivery. They offer superior carrier capacity, specific targeting, and low
toxicity. These advancements have led to significant improvements in stability and absorption efficiency. They
also enhance the ability to reach cellular and intracellular targets with greater effectiveness. However, there are
complex issues regarding toxicity, safety, and production scale of nanoparticles. Resolving these problems could
lead to clinical treatments based on laboratory successes. The next generation of medication delivery systems
could benefit from personalized therapeutic techniques combined with smart nanomaterials. The main aim of
this review is to explore recent developments in the design, synthesis, and optimization of therapeutic nanoparticles. This includes understanding their size, shape, and multifunctional properties to enhance the effectiveness of drug delivery. This review covers various methods for designing and characterizing nanoparticles. It
focuses on optimizing nanostructures for enhanced drug delivery. The synthesis techniques, analysis methods,
and potential modifications of nanoparticle characterization are discussed. Properly synthesized and optimized
therapeutic nanoparticles represent a significant breakthrough in the field of drug delivery systems. Their ability to overcome the limitations of traditional therapies holds promise for future medical applications. Further
research into their characterization and development will enhance clinical relevance and ensure safe, effective
use in therapeutic settings.

Item Type: Article
Subjects: Biotechnology > Microbiology
Biotechnology > Microbiology and Macromolecule
Biotechnology > Molecular Genetics
Biotechnology > Nanotechnology
Biotechnology > Biopharmaceutical Technology
Domains: Biotechnology
Depositing User: Mr IR Admin
Date Deposited: 11 May 2026 08:21
Last Modified: 14 May 2026 12:47
URI: https://ir.vistas.ac.in/id/eprint/16386

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