DESIGN AND NOVEL SYNTHESIS OF SCHIFF BASE DERIVATIVE FOR ANTI VIRAL ACTIVITY

Schiff base derivatives are widely recognized for their significant biological activities,
including antiviral properties. The present study focuses on the design and novel synthesis of
a Schiff base derivative aimed at evaluating its antiviral potential. The compound was
synthesized via condensation reaction between a selected aldehyde and primary amine under
optimized reaction conditions. The synthesized derivative was purified and characterized
using various analytical techniques such as UV-Visible spectroscopy, Infrared (IR)
spectroscopy, and Nuclear Magnetic Resonance (NMR) analysis to confirm its structure. The
antiviral activity of the synthesized compound was assessed against selected viral strains
using standard in vitro methods. The indicated notable inhibitory activity, suggesting its
effectiveness in preventing viral replication. The structure–activity relationship highlights the
importance of functional groups in enhancing antiviral efficacy. Overall, this study suggests
that the newly synthesized Schiff base derivative holds promise as a potential lead compound
for further development of safe and effective antiviral agents