Nanostructured Metal Oxide and Self-Assembled Systems for enhanced Phytochemical Bioavailability

Self-assembled nanostructures and metal oxide nanoparticles have emerged as versatile platforms for advanced biomedical and functional applications. This presentation highlights recent developments in the design, synthesis, and characterization of metal oxide nanoparticles and self-assembled nanosystems aimed at addressing key challenges such as poor solubility, limited stability, and low bioavailability of phytochemicals. Strategies involving controlled self-assembly, surface functionalization, and optimization of nano–bio interactions are discussed to enhance therapeutic efficacy and targeted delivery. Representative studies demonstrate improved bioavailability, sustained release behavior, and enhanced biological performance of phytochemical-loaded nanocarriers. The approaches presented emphasize the potential of nanotechnology-enabled formulations to bridge traditional bioactive compounds with modern materials science, offering promising directions for future translational and device-oriented applications.
Keywords: Metal oxide nanoparticle; Nanoparticles; Self assembled systems.