Formulation And Evaluation Of Herbal Insitu Gel With Gastro Protective Activity

This study shows novel herbal in-situ gel for the prevention and treatment of gastric ulcers is formulated and evaluated.
The study concentrated on utilizing the well known anti-ulcer, anti-inflammatory, and anti-oxidant qualities of jamun
fruit and pomegranate peel natural extracts by combining them in a gel matrix. Using in-situ gelation technology, the gel
increases the bioavailability and effectiveness of the herbal compounds by allowing for targeted and sustained drug release
in response to physiological stimuli like pH and temperature. Several natural polymers were used to optimize the
formulation and both in-vitro and in-vivo techniques were used to evaluate it’s physical, chemical and biological
characteristics. Because of it’s non toxic nature and ease of administration, The results demonstrated notable gastro
protective, healing effects, improved anti-oxidant level and enhanced patient compliance.