Abstract
Food insecurity, environmental degradation, and climate change are among the persistent global challenges facing humanity, and fungi offer unique and underexplored opportunities to address them. Resilient food sources, animal feed, biochemicals, biofuels, textiles, and raw materials for the automotive, construction, and transportation sectors are among the many valuable products that these adaptable organisms can effectively derive from organic materials. Their exceptional metabolic diversity and adaptability make them excellent candidates for industrial applications. The global transition from a petroleum-based economy to a sustainable, bio-based circular economy is being accelerated by advances in fungal biotechnology. Fungal systems contribute to reducing greenhouse gas emissions and environmental pollution by enabling the production of eco-friendly alternatives and promoting efficient resource utilisation. Additionally, by stabilising agricultural systems and enhancing nutrient availability for a growing global population, fungi offer promising strategies to improve food security. Developments in fungal biotechnology, along with the rational design and optimisation of both existing and novel fungal cell factories, hold significant potential to mitigate the effects of climate change. These initiatives are aligned with the United Nations Sustainable Development Goals (SDGs), particularly those related to responsible consumption, climate action, and zero hunger. This chapter summarises current prospects and research challenges in the utilisation of fungal resources for a sustainable and circular economy, aiming to raise awareness among academicians, researchers, industry stakeholders, and policymakers about the ongoing fungal biotechnology revolution.
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References
Abarca, C., Bidondo, L. F., Bompadre, J., & Velázquez, M. S. (2024). Arbuscular mycorrhizal fungi in tomato tolerance to pathogens and nematodes: A comprehensive review. Scientia Horticulturae, 329, 112969.
Aggarwal, S., & Kumari, A. (2024). Role of fungi in biotechnology. In Entrepreneurship with microorganisms (pp. 39–67). Academic.
Ahmad, A., Mustafa, G., Rana, A., & Zia, A. R. (2023). Improvements in bioremediation agents and their modified strains in mediating environmental pollution. Current Microbiology, 80(6), 208.
Alemu, D., Tafesse, M., & Gudetta Deressa, Y. (2022). Production of mycoblock from the mycelium of the fungus Pleurotus ostreatus for use as sustainable construction materials. Advances in Materials Science and Engineering, 2022(1), 2876643.
Bharathi, S. D., & Jacob, S. (2024). Comprehensive treatment strategy for banana inflorescence bract to synthesise biodiesel and bioethanol through fungal biorefinery. Waste and Biomass Valorization, 15(1), 417–436.
Boukary, A. A., Olou, A. B., Piepenbring, M., & Yorou, N. S. (2024). Mushroom cultivation in tropical Africa: Successes, challenges, and opportunities. Journal of Agriculture and Food Research, 101264.
Carvalho, D., Ferreira, N., França, B., Marques, R., Silva, M., Silva, S., & Oliveira, C. (2024). Advancing sustainability in the automotive industry: Bioprepregs and fully bio-based composites. Composites Part C: Open Access, 14, 100459.
Chalakara, A. A., & Thomas, T. (2025). Production kinetics and bioactivity study of Aspulvinone pigment from Aspergillus terreus STCP01 for natural colourant applications. Bioresource Technology Reports, 29, 102042.
Chaparro, M. L., Sanabria, P. J., Jiménez, A. M., Gómez, M. I., Bautista, E. J., & Mesa, L. (2021). A circular economy approach for producing a fungal-based biopesticide employing pearl millet as a substrate and its economic evaluation. Bioresource Technology Reports, 16, 100869.
Elhalis, H. (2025). Exploring fungal mycelium for sustainable food solutions: From biomass utilization to byproduct innovation. Food Reviews International, 1–33.
Engwenyu, L. R., & Anderson, A. S. (2021). A comprehensive review of calcineurin inhibitors used for immunosuppression in cardiac transplantation. Pharmacology of Immunosuppression, 27–38.
Espinosa-Páez, E., Hernández-Luna, C. E., Longoria-García, S., Martínez-Silva, P. A., Ortiz-Rodríguez, I., Villarreal-Vera, M. T., & Cantú-Saldaña, C. M. (2021). Pleurotus ostreatus: A potential concurrent biotransformation agent/ingredient on development of functional foods (cookies). LWT, 148, 111727.
Garg, S., Kim, M., & Romero-Suarez, D. (2024). Current advancements in fungal engineering technologies for sustainable development goals. Trends in Microbiology, 33(3), 285–301.
Gharib, M. A. A., Elhassaneen, Y. A. E. E., & Radwan, H. (2022). Nutrients and nutraceuticals content and in vitro biological activities of reishi mushroom (Ganoderma lucidum) fruiting bodies. Alexandria Science Exchange Journal, 43(2), 301–316.
Hashemi, S. S., Abbasi-Riyakhuni, M., Denayer, J. F., Tabatabaei, M., Aghbashlo, M., & Karimi, K. (2023). Efficient bioremediation of distillery and dairy wastewaters: A three-stage biorefinery for high-quality aquaculture feed and bioenergy generation. Process Safety and Environmental Protection, 180, 566–574.
Hassan, M. (2025). Fungi as potent bioresource for biofuel production. In Fungal biotechnology (pp. 677–694). Academic.
Hu, Y., Du, C., Leu, S. Y., Jing, H., Li, X., & Lin, C. S. K. (2018). Valorisation of textile waste by fungal solid state fermentation: An example of circular waste-based biorefinery. Resources, Conservation and Recycling, 129, 27–35.
Kamande, S. M., Omwenga, G. I., & Ngugi, M. P. (2024). Production of cellulases by Xylaria sp. and Nemania sp. using lignocellulose substrates for bioethanol production from maise cobs. Heliyon, 10(17), e36802.
Khan, M. T., Aleinikovienė, J., & Butkevičienė, L. M. (2024). Innovative organic fertilisers and cover crops: Perspectives for sustainable agriculture in the era of climate change and organic agriculture. Agronomy, 14(12), 2871.
Khatoon, Z., Orozco-Mosqueda, M. D. C., & Santoyo, G. (2024). Microbial contributions to heavy metal phytoremediation in agricultural soils: A review. Microorganisms, 12(10), 1945
Kour, H., Kour, D., Kour, S., Singh, S., Hashmi, S. A. J., Yadav, A. N., & Ahluwalia, A. S. (2022). Bioactive compounds from mushrooms: Emerging bioresources of food and nutraceuticals. Food Bioscience, 50, 102124.
Krishnamoorthi, R., Srinivash, M., Mahalingam, P. U., & Malaikozhundan, B. (2022). Dietary nutrients in edible mushroom, Agaricus bisporus and their radical scavenging, antibacterial, and antifungal effects. Process Biochemistry, 121, 10–17.
Kumar, V., & Dwivedi, S. K. (2020). Multimetal tolerant fungus Aspergillus flavus CR500 with remarkable stress response, simultaneous multiple metal/loid removal ability and bioremediation potential of wastewater. Environmental Technology & Innovation, 20, 101075
Li, H., Tian, Y., Menolli, N., Jr., Ye, L., Karunarathna, S. C., Perez-Moreno, J., & Mortimer, P. E. (2021). Reviewing the world’s edible mushroom species: A new evidence-based classification system. Comprehensive Reviews in Food Science and Food Safety, 20(2), 1982–2014.
Lin, S. Y., Baumann, K., Zhou, C., Zhou, W., Cuellar, A. E., & Xue, H. (2021). Trends in use and expenditures for brand-name statins after introduction of generic statins in the US, 2002-2018. JAMA Network Open, 4(11), e2135371.
Maini Rekdal, V., van der Luijt, C. R., Chen, Y., Kakumanu, R., Baidoo, E. E., Petzold, C. J., & Keasling, J. D. (2024). Edible mycelium bioengineered for enhanced nutritional value and sensory appeal using a modular synthetic biology toolkit. Nature Communications, 15(1), 2099.
Matchado, M. S., Lauber, M., Reitmeier, S., Kacprowski, T., Baumbach, J., Haller, D., & List, M. (2021). Network analysis methods for studying microbial communities: A mini review. Computational and Structural Biotechnology Journal, 19, 2687–2698.
Mayirnao, H. S., Sharma, K., Jangir, P., Kaur, S., & Kapoor, R. (2025). Mushroom-derived nutraceuticals in the 21st century: An appraisal and future perspectives. Journal of Future Foods, 5(4), 342–360.
Monclaro, A. V., Gomes, H. A. R., Duarte, G. C., de Souza Moreira, L. R., & Filho, E. X. F. (2024). Unveiling the biomass valorization: The microbial diversity in promoting a sustainable socio-economy. Bioenergy Research, 17(3), 1355–1374.
Ojwach, J., Adetunji, A. I., Mutanda, T., & Mukaratirwa, S. (2022). Oligosaccharides production from coprophilous fungi: An emerging functional food with potential health-promoting properties. Biotechnology Reports, 33, e00702.
Patel, J. Y., & Sharma, J. (2023). A review of mycelium-based bio-composites and their possible application in architecture. ShodhKosh: Journal of Visual and Performing Arts, 4, 213–225.
Periyasamy, S., Isabel, J. B., Kavitha, S., Karthik, V., Mohamed, B. A., Gizaw, D. G., & Aminabhavi, T. M. (2023). Recent advances in consolidated bioprocessing for conversion of lignocellulosic biomass into bioethanol–A review. Chemical Engineering Journal, 453, 139783.
Prescott, T. A., Hill, R., Mas-Claret, E., Gaya, E., & Burns, E. (2023). Fungal drug discovery for chronic disease: History, new discoveries and new approaches. Biomolecules, 13(6), 986.
Rahamim, V., Nakonechny, F., Azagury, A., & Nisnevitch, M. (2022). Continuous bioethanol production by fungi and yeast working in Tandem. Energies, 15(12), 4338.
Rajhans, G., Sen, S. K., Barik, A., & Raut, S. (2021). De-colourisation of textile effluent using immobilised Geotrichum candidum: An insight into mycoremediation. Letters in Applied Microbiology, 72(4), 445–457.
Rashad, M., Kenawy, E. R., Hosny, A., Hafez, M., & Elbana, M. (2021). An environmental friendly superabsorbent composite based on rice husk as soil amendment to improve plant growth and water productivity under deficit irrigation conditions. Journal of Plant Nutrition, 44(7), 1010–1022.
Robey, M. T., Caesar, L. K., Drott, M. T., Keller, N. P., & Kelleher, N. L. (2021). An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes. Proceedings of the National Academy of Sciences, 118(19), e2020230118.
Rousta, N., Aslan, M., Yesilcimen Akbas, M., Ozcan, F., Sar, T., & Taherzadeh, M. J. (2024). Effects of fungal based bioactive compounds on human health. Critical Reviews in Food Science and Nutrition, 64(20), 7004–7027.
Ruangwicha, J., Cheirsilp, B., & Suyotha, W. (2024). Green biorefinery of shrimp shell waste for α-chitin and high-value co-products through successive fermentation by co-lactic acid bacteria and proteolytic fungus. Bioresource Technology, 393, 130106.
Saeed, Z., Cheirsilp, B., Maneechote, W., Kongjan, P., & Jariyaboon, R. (2024). Optimising bioencapsulation of yeast cells by Aspergillus tubingensis TSIP9 and applications in bioethanol production through repeated-batch fermentation. Biocatalysis and Agricultural Biotechnology, 61, 103377.
Sansinenea, E. (2021). Application of biofertilisers: Current worldwide status. In Biofertilizers (pp. 183–190). Woodhead Publishing.
Sawant, A., & Sajwan, H. (2022). Fungal metabolites: Industrial applications and challenges. Sustainable Utilization of Fungi in Agriculture and Industry, 159–201.
Shankar, A., Saini, S., & Sharma, K. K. (2024). Fungal-integrated second-generation lignocellulosic biorefinery: Utilisation of agricultural biomass for co-production of lignocellulolytic enzymes, mushroom, fungal polysaccharides, and bioethanol. Biomass Conversion and Biorefinery, 14(1), 1117–1131.
Sharma, R., & Sumbria, R. (2022). Mycelium bricks and composites for sustainable construction industry: A state-of-the-art review. Innovative Infrastructure Solutions, 7(5), 298.
Sharma, R., Khatua, S., Acharya, K., & Sharma, Y. P. (2022). Mycochemical composition and antioxidant activity of Flammulina velutipes: A comparative study on hydromethanol, decoction and infusion extracts. Vegetos, 35(3), 607–613.
Sharma, E., Bairwa, R., Lal, P., Pattanayak, S., Chakrapani, K., Poorvasandhya, R., & Kumar, R. (2024). Edible mushrooms trending in food: Nutrigenomics, bibliometric, from bench to valuable applications. Heliyon, 10(17), e36963.
Shinde, R., Shahi, D. K., Mahapatra, P., Singh, C. S., Naik, S. K., Thombare, N., & Singh, A. K. (2022). Management of crop residues with special reference to the on-farm utilization methods: A review. Industrial Crops and Products, 181, 114772.
Shuting, C. (2024). Mushrooms: Fungi for all seasons. Acta Edulis Fungi, 31(1).
Silvestri, L. (2022). Terraforma-material investigation on the possibilities to combine natural growth of mycelium and unfired clay for novel sustainable product design applications.
Srivastava, S., Mathur, P., Prakash, P., Falletta, E., Katha, U., Pagani, A., & Singh, A. V. (2025). Mushroom-derived innovations: Sustainable biomaterials for biomedical engineering. Biomedical Materials and Devices, 3(1), 381–395.
Svensson, S. E., Bucuricova, L., Ferreira, J. A., Souza Filho, P. F., Taherzadeh, M. J., & Zamani, A. (2021). Valorisation of bread waste to a fiber-and protein-rich fungal biomass. Fermentation, 7(2), 91.
Svensson, S. E., Abdollahi, M., Moghadam, F. H., Kalita, N. K., Hakkarainen, M., Wijayarathna, E. K. B., & Zamani, A. (2024). Valorisation of bread waste to fungal-based products for medical textile and food applications. ACS Sustainable Resource Management, 1(3), 385–394.
Tiwari, P., & Park, K. I. (2024). Advanced fungal biotechnologies in accomplishing sustainable development goals (SDGs): What do we know and what comes next? Journal of Fungi, 10(7), 506.
Torres-Farradá, G., Thijs, S., Rineau, F., Guerra, G., & Vangronsveld, J. (2024). White rot fungi as tools for the bioremediation of xenobiotics: A review. Journal of Fungi, 10(3), 167.
Usman, M., Murtaza, G., & Ditta, A. (2021). Nutritional, medicinal, and cosmetic value of bioactive compounds in button mushroom (Agaricus bisporus): A review. Applied Sciences, 11(13), 5943.
Voutetaki, M. E., & Mpalaskas, A. C. (2024). Natural fiber-reinforced mycelium composite for innovative and sustainable construction materials. Fibers, 12(7), 57.
Wadhwa, K., Kapoor, N., Kaur, H., Abu-Seer, E. A., Tariq, M., Siddiqui, S., & Alghamdi, S. (2024). A comprehensive review of the diversity of fungal secondary metabolites and their emerging applications in healthcare and environment. Mycobiology, 52, 1–53.
Wang, Y., Liu, Z., Hao, X., Wang, Z., Wang, Z., Liu, S., & Li, R. (2023). Biodiversity of the beneficial soil-borne fungi steered by Trichoderma-amended biofertilisers stimulates plant production. npj Biofilms and Microbiomes, 9(1), 46.
Yağmur, A., Demir, S., Canpolat, S., Rezaee Danesh, Y., Farda, B., Djebaili, R., & Pellegrini, M. (2024). Onion Fusarium basal rot disease control by arbuscular mycorrhizal fungi and Trichoderma harzianum. Plants, 13(3), 386.
Yang, Y., Zhang, X., Hartley, I. P., Dungait, J. A., Wen, X., Li, D., & Quine, T. A. (2022). Contrasting rhizosphere soil nutrient economy of plants associated with arbuscular mycorrhizal and ectomycorrhizal fungi in karst forests. Plant and Soil, 470(1), 81–93.
Yi, D., Bayer, T., Badenhorst, C. P., Wu, S., Doerr, M., Höhne, M., & Bornscheuer, U. T. (2021). Recent trends in biocatalysis. Chemical Society Reviews, 50(14), 8003–8049.
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Ramalakshmi, S., Helan Chandra, J., Sivasubramanian, K., Arvind Bharani, R.S., Lekhavani, R., Suguna, K. (2026). Recent Innovations in Myco-biotechnology: Valourisation of Fungal Resources for a Sustainable and a Circular Economy. In: Gupta, A. (eds) Prospects of Fungal Biotechnologies for Livestock Volume 2. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-032-06478-3_7
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