Skip to main content

Recent Innovations in Myco-biotechnology: Valourisation of Fungal Resources for a Sustainable and a Circular Economy

  • Chapter
  • First Online:
Prospects of Fungal Biotechnologies for Livestock Volume 2

Part of the book series: Fungal Biology ((FUNGBIO))

  • 109 Accesses

Abstract

Food insecurity, environmental degradation, and climate change are among the persistent global challenges facing humanity, and fungi offer unique and underexplored opportunities to address them. Resilient food sources, animal feed, biochemicals, biofuels, textiles, and raw materials for the automotive, construction, and transportation sectors are among the many valuable products that these adaptable organisms can effectively derive from organic materials. Their exceptional metabolic diversity and adaptability make them excellent candidates for industrial applications. The global transition from a petroleum-based economy to a sustainable, bio-based circular economy is being accelerated by advances in fungal biotechnology. Fungal systems contribute to reducing greenhouse gas emissions and environmental pollution by enabling the production of eco-friendly alternatives and promoting efficient resource utilisation. Additionally, by stabilising agricultural systems and enhancing nutrient availability for a growing global population, fungi offer promising strategies to improve food security. Developments in fungal biotechnology, along with the rational design and optimisation of both existing and novel fungal cell factories, hold significant potential to mitigate the effects of climate change. These initiatives are aligned with the United Nations Sustainable Development Goals (SDGs), particularly those related to responsible consumption, climate action, and zero hunger. This chapter summarises current prospects and research challenges in the utilisation of fungal resources for a sustainable and circular economy, aiming to raise awareness among academicians, researchers, industry stakeholders, and policymakers about the ongoing fungal biotechnology revolution.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+
from €37.37 /Month
  • Starting from 10 chapters or articles per month
  • Access and download chapters and articles from more than 300k books and 2,500 journals
  • Cancel anytime
View plans

Buy Now

Chapter
EUR 29.95
Price includes VAT (India)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
EUR 171.19
Price includes VAT (India)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
EUR 199.99
Price excludes VAT (India)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Abarca, C., Bidondo, L. F., Bompadre, J., & Velázquez, M. S. (2024). Arbuscular mycorrhizal fungi in tomato tolerance to pathogens and nematodes: A comprehensive review. Scientia Horticulturae, 329, 112969.

    Article  CAS  Google Scholar 

  • Aggarwal, S., & Kumari, A. (2024). Role of fungi in biotechnology. In Entrepreneurship with microorganisms (pp. 39–67). Academic.

    Chapter  Google Scholar 

  • Ahmad, A., Mustafa, G., Rana, A., & Zia, A. R. (2023). Improvements in bioremediation agents and their modified strains in mediating environmental pollution. Current Microbiology, 80(6), 208.

    Article  CAS  PubMed  Google Scholar 

  • Alemu, D., Tafesse, M., & Gudetta Deressa, Y. (2022). Production of mycoblock from the mycelium of the fungus Pleurotus ostreatus for use as sustainable construction materials. Advances in Materials Science and Engineering, 2022(1), 2876643.

    Google Scholar 

  • Bharathi, S. D., & Jacob, S. (2024). Comprehensive treatment strategy for banana inflorescence bract to synthesise biodiesel and bioethanol through fungal biorefinery. Waste and Biomass Valorization, 15(1), 417–436.

    Article  CAS  Google Scholar 

  • Boukary, A. A., Olou, A. B., Piepenbring, M., & Yorou, N. S. (2024). Mushroom cultivation in tropical Africa: Successes, challenges, and opportunities. Journal of Agriculture and Food Research, 101264.

    Google Scholar 

  • Carvalho, D., Ferreira, N., França, B., Marques, R., Silva, M., Silva, S., & Oliveira, C. (2024). Advancing sustainability in the automotive industry: Bioprepregs and fully bio-based composites. Composites Part C: Open Access, 14, 100459.

    CAS  Google Scholar 

  • Chalakara, A. A., & Thomas, T. (2025). Production kinetics and bioactivity study of Aspulvinone pigment from Aspergillus terreus STCP01 for natural colourant applications. Bioresource Technology Reports, 29, 102042.

    Article  Google Scholar 

  • Chaparro, M. L., Sanabria, P. J., Jiménez, A. M., Gómez, M. I., Bautista, E. J., & Mesa, L. (2021). A circular economy approach for producing a fungal-based biopesticide employing pearl millet as a substrate and its economic evaluation. Bioresource Technology Reports, 16, 100869.

    Article  CAS  Google Scholar 

  • Elhalis, H. (2025). Exploring fungal mycelium for sustainable food solutions: From biomass utilization to byproduct innovation. Food Reviews International, 1–33.

    Google Scholar 

  • Engwenyu, L. R., & Anderson, A. S. (2021). A comprehensive review of calcineurin inhibitors used for immunosuppression in cardiac transplantation. Pharmacology of Immunosuppression, 27–38.

    Google Scholar 

  • Espinosa-Páez, E., Hernández-Luna, C. E., Longoria-García, S., Martínez-Silva, P. A., Ortiz-Rodríguez, I., Villarreal-Vera, M. T., & Cantú-Saldaña, C. M. (2021). Pleurotus ostreatus: A potential concurrent biotransformation agent/ingredient on development of functional foods (cookies). LWT, 148, 111727.

    Article  Google Scholar 

  • Garg, S., Kim, M., & Romero-Suarez, D. (2024). Current advancements in fungal engineering technologies for sustainable development goals. Trends in Microbiology, 33(3), 285–301.

    Article  PubMed  Google Scholar 

  • Gharib, M. A. A., Elhassaneen, Y. A. E. E., & Radwan, H. (2022). Nutrients and nutraceuticals content and in vitro biological activities of reishi mushroom (Ganoderma lucidum) fruiting bodies. Alexandria Science Exchange Journal, 43(2), 301–316.

    Article  Google Scholar 

  • Hashemi, S. S., Abbasi-Riyakhuni, M., Denayer, J. F., Tabatabaei, M., Aghbashlo, M., & Karimi, K. (2023). Efficient bioremediation of distillery and dairy wastewaters: A three-stage biorefinery for high-quality aquaculture feed and bioenergy generation. Process Safety and Environmental Protection, 180, 566–574.

    Article  CAS  Google Scholar 

  • Hassan, M. (2025). Fungi as potent bioresource for biofuel production. In Fungal biotechnology (pp. 677–694). Academic.

    Chapter  Google Scholar 

  • Hu, Y., Du, C., Leu, S. Y., Jing, H., Li, X., & Lin, C. S. K. (2018). Valorisation of textile waste by fungal solid state fermentation: An example of circular waste-based biorefinery. Resources, Conservation and Recycling, 129, 27–35.

    Google Scholar 

  • Kamande, S. M., Omwenga, G. I., & Ngugi, M. P. (2024). Production of cellulases by Xylaria sp. and Nemania sp. using lignocellulose substrates for bioethanol production from maise cobs. Heliyon, 10(17), e36802.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Khan, M. T., Aleinikovienė, J., & Butkevičienė, L. M. (2024). Innovative organic fertilisers and cover crops: Perspectives for sustainable agriculture in the era of climate change and organic agriculture. Agronomy, 14(12), 2871.

    Article  CAS  Google Scholar 

  • Khatoon, Z., Orozco-Mosqueda, M. D. C., & Santoyo, G. (2024). Microbial contributions to heavy metal phytoremediation in agricultural soils: A review. Microorganisms, 12(10), 1945

    Google Scholar 

  • Kour, H., Kour, D., Kour, S., Singh, S., Hashmi, S. A. J., Yadav, A. N., & Ahluwalia, A. S. (2022). Bioactive compounds from mushrooms: Emerging bioresources of food and nutraceuticals. Food Bioscience, 50, 102124.

    Article  CAS  Google Scholar 

  • Krishnamoorthi, R., Srinivash, M., Mahalingam, P. U., & Malaikozhundan, B. (2022). Dietary nutrients in edible mushroom, Agaricus bisporus and their radical scavenging, antibacterial, and antifungal effects. Process Biochemistry, 121, 10–17.

    Article  CAS  Google Scholar 

  • Kumar, V., & Dwivedi, S. K. (2020). Multimetal tolerant fungus Aspergillus flavus CR500 with remarkable stress response, simultaneous multiple metal/loid removal ability and bioremediation potential of wastewater. Environmental Technology & Innovation, 20, 101075

    Google Scholar 

  • Li, H., Tian, Y., Menolli, N., Jr., Ye, L., Karunarathna, S. C., Perez-Moreno, J., & Mortimer, P. E. (2021). Reviewing the world’s edible mushroom species: A new evidence-based classification system. Comprehensive Reviews in Food Science and Food Safety, 20(2), 1982–2014.

    Article  PubMed  Google Scholar 

  • Lin, S. Y., Baumann, K., Zhou, C., Zhou, W., Cuellar, A. E., & Xue, H. (2021). Trends in use and expenditures for brand-name statins after introduction of generic statins in the US, 2002-2018. JAMA Network Open, 4(11), e2135371.

    Article  PubMed  PubMed Central  Google Scholar 

  • Maini Rekdal, V., van der Luijt, C. R., Chen, Y., Kakumanu, R., Baidoo, E. E., Petzold, C. J., & Keasling, J. D. (2024). Edible mycelium bioengineered for enhanced nutritional value and sensory appeal using a modular synthetic biology toolkit. Nature Communications, 15(1), 2099.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Matchado, M. S., Lauber, M., Reitmeier, S., Kacprowski, T., Baumbach, J., Haller, D., & List, M. (2021). Network analysis methods for studying microbial communities: A mini review. Computational and Structural Biotechnology Journal, 19, 2687–2698.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mayirnao, H. S., Sharma, K., Jangir, P., Kaur, S., & Kapoor, R. (2025). Mushroom-derived nutraceuticals in the 21st century: An appraisal and future perspectives. Journal of Future Foods, 5(4), 342–360.

    Article  CAS  Google Scholar 

  • Monclaro, A. V., Gomes, H. A. R., Duarte, G. C., de Souza Moreira, L. R., & Filho, E. X. F. (2024). Unveiling the biomass valorization: The microbial diversity in promoting a sustainable socio-economy. Bioenergy Research, 17(3), 1355–1374.

    Article  Google Scholar 

  • Ojwach, J., Adetunji, A. I., Mutanda, T., & Mukaratirwa, S. (2022). Oligosaccharides production from coprophilous fungi: An emerging functional food with potential health-promoting properties. Biotechnology Reports, 33, e00702.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Patel, J. Y., & Sharma, J. (2023). A review of mycelium-based bio-composites and their possible application in architecture. ShodhKosh: Journal of Visual and Performing Arts, 4, 213–225.

    Google Scholar 

  • Periyasamy, S., Isabel, J. B., Kavitha, S., Karthik, V., Mohamed, B. A., Gizaw, D. G., & Aminabhavi, T. M. (2023). Recent advances in consolidated bioprocessing for conversion of lignocellulosic biomass into bioethanol–A review. Chemical Engineering Journal, 453, 139783.

    Article  CAS  Google Scholar 

  • Prescott, T. A., Hill, R., Mas-Claret, E., Gaya, E., & Burns, E. (2023). Fungal drug discovery for chronic disease: History, new discoveries and new approaches. Biomolecules, 13(6), 986.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rahamim, V., Nakonechny, F., Azagury, A., & Nisnevitch, M. (2022). Continuous bioethanol production by fungi and yeast working in Tandem. Energies, 15(12), 4338.

    Article  CAS  Google Scholar 

  • Rajhans, G., Sen, S. K., Barik, A., & Raut, S. (2021). De-colourisation of textile effluent using immobilised Geotrichum candidum: An insight into mycoremediation. Letters in Applied Microbiology, 72(4), 445–457.

    Article  CAS  PubMed  Google Scholar 

  • Rashad, M., Kenawy, E. R., Hosny, A., Hafez, M., & Elbana, M. (2021). An environmental friendly superabsorbent composite based on rice husk as soil amendment to improve plant growth and water productivity under deficit irrigation conditions. Journal of Plant Nutrition, 44(7), 1010–1022.

    Article  CAS  Google Scholar 

  • Robey, M. T., Caesar, L. K., Drott, M. T., Keller, N. P., & Kelleher, N. L. (2021). An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes. Proceedings of the National Academy of Sciences, 118(19), e2020230118.

    Article  CAS  Google Scholar 

  • Rousta, N., Aslan, M., Yesilcimen Akbas, M., Ozcan, F., Sar, T., & Taherzadeh, M. J. (2024). Effects of fungal based bioactive compounds on human health. Critical Reviews in Food Science and Nutrition, 64(20), 7004–7027.

    Article  PubMed  Google Scholar 

  • Ruangwicha, J., Cheirsilp, B., & Suyotha, W. (2024). Green biorefinery of shrimp shell waste for α-chitin and high-value co-products through successive fermentation by co-lactic acid bacteria and proteolytic fungus. Bioresource Technology, 393, 130106.

    Article  CAS  PubMed  Google Scholar 

  • Saeed, Z., Cheirsilp, B., Maneechote, W., Kongjan, P., & Jariyaboon, R. (2024). Optimising bioencapsulation of yeast cells by Aspergillus tubingensis TSIP9 and applications in bioethanol production through repeated-batch fermentation. Biocatalysis and Agricultural Biotechnology, 61, 103377.

    Article  CAS  Google Scholar 

  • Sansinenea, E. (2021). Application of biofertilisers: Current worldwide status. In Biofertilizers (pp. 183–190). Woodhead Publishing.

    Chapter  Google Scholar 

  • Sawant, A., & Sajwan, H. (2022). Fungal metabolites: Industrial applications and challenges. Sustainable Utilization of Fungi in Agriculture and Industry, 159–201.

    Google Scholar 

  • Shankar, A., Saini, S., & Sharma, K. K. (2024). Fungal-integrated second-generation lignocellulosic biorefinery: Utilisation of agricultural biomass for co-production of lignocellulolytic enzymes, mushroom, fungal polysaccharides, and bioethanol. Biomass Conversion and Biorefinery, 14(1), 1117–1131.

    Article  CAS  Google Scholar 

  • Sharma, R., & Sumbria, R. (2022). Mycelium bricks and composites for sustainable construction industry: A state-of-the-art review. Innovative Infrastructure Solutions, 7(5), 298.

    Article  Google Scholar 

  • Sharma, R., Khatua, S., Acharya, K., & Sharma, Y. P. (2022). Mycochemical composition and antioxidant activity of Flammulina velutipes: A comparative study on hydromethanol, decoction and infusion extracts. Vegetos, 35(3), 607–613.

    Article  Google Scholar 

  • Sharma, E., Bairwa, R., Lal, P., Pattanayak, S., Chakrapani, K., Poorvasandhya, R., & Kumar, R. (2024). Edible mushrooms trending in food: Nutrigenomics, bibliometric, from bench to valuable applications. Heliyon, 10(17), e36963.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shinde, R., Shahi, D. K., Mahapatra, P., Singh, C. S., Naik, S. K., Thombare, N., & Singh, A. K. (2022). Management of crop residues with special reference to the on-farm utilization methods: A review. Industrial Crops and Products, 181, 114772.

    Article  Google Scholar 

  • Shuting, C. (2024). Mushrooms: Fungi for all seasons. Acta Edulis Fungi, 31(1).

    Google Scholar 

  • Silvestri, L. (2022). Terraforma-material investigation on the possibilities to combine natural growth of mycelium and unfired clay for novel sustainable product design applications.

    Google Scholar 

  • Srivastava, S., Mathur, P., Prakash, P., Falletta, E., Katha, U., Pagani, A., & Singh, A. V. (2025). Mushroom-derived innovations: Sustainable biomaterials for biomedical engineering. Biomedical Materials and Devices, 3(1), 381–395.

    Article  Google Scholar 

  • Svensson, S. E., Bucuricova, L., Ferreira, J. A., Souza Filho, P. F., Taherzadeh, M. J., & Zamani, A. (2021). Valorisation of bread waste to a fiber-and protein-rich fungal biomass. Fermentation, 7(2), 91.

    Article  CAS  Google Scholar 

  • Svensson, S. E., Abdollahi, M., Moghadam, F. H., Kalita, N. K., Hakkarainen, M., Wijayarathna, E. K. B., & Zamani, A. (2024). Valorisation of bread waste to fungal-based products for medical textile and food applications. ACS Sustainable Resource Management, 1(3), 385–394.

    Article  CAS  Google Scholar 

  • Tiwari, P., & Park, K. I. (2024). Advanced fungal biotechnologies in accomplishing sustainable development goals (SDGs): What do we know and what comes next? Journal of Fungi, 10(7), 506.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Torres-Farradá, G., Thijs, S., Rineau, F., Guerra, G., & Vangronsveld, J. (2024). White rot fungi as tools for the bioremediation of xenobiotics: A review. Journal of Fungi, 10(3), 167.

    Article  PubMed  PubMed Central  Google Scholar 

  • Usman, M., Murtaza, G., & Ditta, A. (2021). Nutritional, medicinal, and cosmetic value of bioactive compounds in button mushroom (Agaricus bisporus): A review. Applied Sciences, 11(13), 5943.

    Article  CAS  Google Scholar 

  • Voutetaki, M. E., & Mpalaskas, A. C. (2024). Natural fiber-reinforced mycelium composite for innovative and sustainable construction materials. Fibers, 12(7), 57.

    Article  CAS  Google Scholar 

  • Wadhwa, K., Kapoor, N., Kaur, H., Abu-Seer, E. A., Tariq, M., Siddiqui, S., & Alghamdi, S. (2024). A comprehensive review of the diversity of fungal secondary metabolites and their emerging applications in healthcare and environment. Mycobiology, 52, 1–53.

    Article  Google Scholar 

  • Wang, Y., Liu, Z., Hao, X., Wang, Z., Wang, Z., Liu, S., & Li, R. (2023). Biodiversity of the beneficial soil-borne fungi steered by Trichoderma-amended biofertilisers stimulates plant production. npj Biofilms and Microbiomes, 9(1), 46.

    Article  PubMed  PubMed Central  Google Scholar 

  • Yağmur, A., Demir, S., Canpolat, S., Rezaee Danesh, Y., Farda, B., Djebaili, R., & Pellegrini, M. (2024). Onion Fusarium basal rot disease control by arbuscular mycorrhizal fungi and Trichoderma harzianum. Plants, 13(3), 386.

    Article  PubMed  PubMed Central  Google Scholar 

  • Yang, Y., Zhang, X., Hartley, I. P., Dungait, J. A., Wen, X., Li, D., & Quine, T. A. (2022). Contrasting rhizosphere soil nutrient economy of plants associated with arbuscular mycorrhizal and ectomycorrhizal fungi in karst forests. Plant and Soil, 470(1), 81–93.

    Article  CAS  Google Scholar 

  • Yi, D., Bayer, T., Badenhorst, C. P., Wu, S., Doerr, M., Höhne, M., & Bornscheuer, U. T. (2021). Recent trends in biocatalysis. Chemical Society Reviews, 50(14), 8003–8049.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgement

The authors express sincere gratitude to the editors for their kind invitation and guidance, and to all colleagues and collaborators whose insights and support contributed to the completion of this chapter.

Ethical Statement

The authors declare no ethical concerns related to the content presented in this manuscript.

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2026 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Ramalakshmi, S., Helan Chandra, J., Sivasubramanian, K., Arvind Bharani, R.S., Lekhavani, R., Suguna, K. (2026). Recent Innovations in Myco-biotechnology: Valourisation of Fungal Resources for a Sustainable and a Circular Economy. In: Gupta, A. (eds) Prospects of Fungal Biotechnologies for Livestock Volume 2. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-032-06478-3_7

Download citation

Keywords

Publish with us

Policies and ethics